This shows hair shafts (arrows) formed by induced pluripotent stem cell -
derived epithelial stem cells.
Not exact matches
In this pilot study to test the safety of putting iPS -
derived cells into humans, the six are all receiving a graft of new retinal pigment
epithelial cells, which serve to maintain the eye's light - sensing cells.
The study, which followed four individuals for a year after they were treated with embryonic stem cell -
derived retinal pigment
epithelial cells for macular degeneration, observed no serious side effects (tumor growth or other unexpected effects) related to the therapy.
This study aimed to determine whether
epithelial -
derived MMP9 has a defensive role of tumor suppressor in CAC and the underlying molecular mechanism.
Previous studies have shown that MMP9
derived from
epithelial cells plays a protective role in the development of CAC.
In addition, they found that
epithelial -
derived MMP9 suppresses tumors in CAC by activating the MMP9 - Notch1 - ARF - p53 axis pathway, which increases apoptosis, initiates cell cycle arrest and keeps a check on DNA damage.
He and his colleagues will inject into patients» eyes retinal pigment
epithelial cells that ACT
derived from hES cells.
This is a scanning electron microscope image of retinal pigment
epithelial cells
derived from stem cells.
His recent published work describes the rescued visual function in animals using retinal pigment
epithelial cells
derived from human embryonic stem cells and a method for
deriving stem cells using a single - cell approach that does not harm embryos.
The virulence effects of H pylori have been shown to
derive from bacterium factors causing alterations in gastric
epithelial cells.
MimEX ™ Tissue Model Systems provide a robust system to generate accessible ex vivo 3 - D tissue from
epithelial -
derived organs.
This video provides an overview of MimEX ™ Tissue Model Systems, a next - generation 3 - dimensional (3 - D) cell culture platform for the generation of ex vivo
epithelial -
derived organ tissue.
0 Research ArticleRETINAL DISEASES Human ESC —
derived retinal
epithelial cell sheets potentiate rescue of photoreceptor cell loss in rats with retinal degeneration Karim Ben M'Barek 1,2,3, Walter Habeler1, 2,3, Alexandra Plancheron1, 2,3,
Oxidized phospholipids
derived from ozone - treated lung surfactant extract reduce macrophage and
epithelial cell viability.
Cytoplasmic NOTCH and membrane
derived β - catenin link fate choice to
epithelial - mesenchymal transition during myogenesis
SDF - 1 is expressed in synovial
epithelial cells and it has been reported that persistent induction of CXCR4 by stromal
derived factors, such as TGF - β led to SDF - 1 mediated accumulation of CD4 T cells within the rheumatoid joint [44].
Xeno - Free and Defined Human Embryonic Stem Cell -
Derived Retinal Pigment
Epithelial Cells Functionally Integrate in a Large - Eyed Preclinical Model
Matriptase is an
epithelial -
derived, cell surface serine protease.
Innate immune mediator profiles and their regulation in a novel polarized immortalized
epithelial cell model
derived from human endocervix.
The researchers conclude that this could be owing to the bone marrow -
derived MSCs being able to act as progenitor cells, similar to alveolar
epithelial type II cells.
The HUB is founded on the pioneering work of Hans Clevers, M.D., Ph.D., who discovered methods to grow stem cell -
derived human
epithelial mini-organs from the tissues of patients with various diseases.
Nine out of 10 ovarian cancers are
epithelial,
deriving from the outer layer of the ovary.
Stephen Alexander, UK - Cannabinoid receptors, transporters, endocannabinoid turnover, hydrogen sulphide turnover Arthur Christopoulos, Australia (GPCRs Liaison)- G protein - coupled receptors; analytical pharmacology; allosteric modulation; biased agonism; drug discovery; neuropharmacology John Cidlowski, USA (NHRs Liaison)- Glucocorticoid receptor signaling; apoptosis and the immune system Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison) Doriano Fabbro, Switzerland - Kinases and their biology, kinase inhibitors, drug discovery, pharmacology of drugs (kinase inhibitors) in the indication oncology, biology of oncology Kozo Kaibuchi, Japan Yoshikatsu Kanai, Japan - Transporters, amino acid signals,
epithelial function, cancer biology Francesca Levi - Schaffer, Israel - eosinophils and mast cells as effector cells in allergic inflammation: characterization of new receptors / ligands, hypoxia / angiogenesis and eosinophils, asthma, atopic dermatitis, allergic rhinitis, immunopharmacological modulation of allergic diseases by bispecific recombinant antibodies, bacteria interactions with eosinophils and mast cells, the allergic effector unit, mast cell
derived tumors: new antibody based treatment, the allergic inflammation and the resolvome, non IgE - mediated mast cell activation in diseases Eliot H. Ohlstein, USA (Editor)- Drug discovery and development, urogenital biology, cardiovascular / metabolic medicine John A. Peters, UK (LGICs Liaison) Alex Phipps, UK - Oncology, Clinical Pharmacology, Biologics and Immunotherapy Joerg Striessnig, Austria (VGICs Liaison)- Physiology, pharmacology and pathophysiological role of voltage-gated calcium channels
Liu JF, Palakurthi S, Zeng Q, Zhou S, Ivanova E, Huang W, Zervantonakis IK, Selfors LM, Shen Y, Pritchard CC, Zheng M, Adleff V, Papp E, Piao H, Novak M, Fotheringham S, Wulf G, English J, Kirschmeier PT, Velculescu VE, Paweletz CP, Mills GB, Livingston DM, Brugge JS, Matulonis UA, Drapkin R.: Establishment of patient -
derived tumor xenograft models of
epithelial ovarian cancer for pre-clinical evaluation of novel therapeutics.
These results therefore contradict the model
derived from the in vitro data, and indicate that maybe this is not the case in mammary
epithelial SC.