Sentences with phrase «derived hematopoietic»

Microarray profiling using the Affymetrix Mouse Genome 430 2.0 array, defines sets of genes that are specific to bone marrow - derived hematopoietic stem cells and their different immunological progeny.

Using ES cell - derived hematopoietic cells to achieve mixed chimerism would provide the opportunity to accomplish immunological tolerance without the need for harsh host pre-conditioning.

On long - term monitoring, HPC - derived hematopoietic cells remained detectable in both the allogenic and syngeneic mice, albeit declining with time.

The increase in expression of donor type MHC antigens on the HPC - derived hematopoietic cells was gradual.

For example, earlier experiments by others revealed poor engraftment of ES - derived hematopoietic cells in Rag - deficient mice.

Shier LR, Schultz KR, Imren S, Regan J, Issekutz A, Sadek I, Gilman A, Panzarella T, Eaves CJ, Couban S. Differential Effects of G - CSF on Marrow and Blood - Derived Hematopoietic and Immune Cell Populations in Healthy Human Donors.

The FDA has approved the use of stem cell - based products, including cord blood - derived hematopoietic progenitor cells (blood forming stem cells) for many diseases.

Not exact matches

Human hematopoietic stem and progenitor cells (HSPCs), derived from bone marrow, have become a primary vehicle for efforts to replace or regenerate cells destroyed by a variety of diseases.

Hematopoietic stem cells — bone marrow - derived adult stem cells that give rise to the wide variety of specialized blood cells — come in two flavors: the reserve force sits quietly waiting to be called upon while the active arm continually proliferates spawning billions of blood cells every day.

The discovery could provide insight for using megakaryocyte - derived factors, such as TGF - B1 and FGF1, clinically to facilitate regeneration of hematopoietic stem cells, he adds.

The chemokine receptor CXCR - 4 is expressed on CD34 + hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell - derived factor - 1.

Furthermore, these potentials are expanded by the notion that MSCs can exert functions other than those classically attributed to stem or progenitor cells, including establishment and support of the hematopoietic microenvironment in vivo, as observed for bone marrow derived MSCs.

Hematopoietic cell - derived microparticle tissue factor contributes to fibrin formation during thrombus propagation.

Bone marrow derived - hematopoietic stem cells (HSCs) were the first stem cells to be identified and to reach the clinic.

University of Texas M.D. Anderson Cancer Center Tumor - specific alloantigen - anergic donor - derived T - cell therapy after hematopoietic stem - cell transplantation

However, here, we used a well - defined hematopoietic cell population derived from ES cells, and we showed the kinetics of their MHC expression.

Previously the long - term benefits of hematopoietic stem - cell transplantation in cerebral adrenoleukodystrophy (ALD) are thought to be mediated by donor - derived replacement of myeloid derived cells, possibly including microglial cells.

While Wang et al. [12] recently showed no expansion advantage of hematopoietic cells derived from human ES cells, Bowles and colleagues [13] saw increased expansion.

The Workshop on Inherited Hematopoietic Malignancies will discuss the scientific advances in understanding the pathogenesis of cancer development in individuals and families with germline mutations and predisposition to bone marrow derived malignancies.

The researchers advised establishing what kind of stem cells, bone marrow, placenta - derived or hematopoietic, could be best for treating type 2 diabetes.