A glomerulus - on - a-chip lined by human stem cell -
derived kidney cells could help model patient - specific kidney diseases and guide therapeutic discovery
Not exact matches
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic
kidney cells, brain
cell samples and neurons
derived from the stem
cells of healthy people and those with spinal muscular atrophy type I and II.
Gather and Yun did this with
cells derived from a human
kidney, adding the DNA that codes for GFP.
In the longer term, these methods could hasten progress toward replacing a damaged or diseased
kidney with tissue
derived from a patient's own
cells.
«Investigators create complex
kidney structures from human stem
cells derived from adults: New technique offers model for studying disease, progress toward
cell therapy.»
Derived mostly from human embryonic
kidney 293T (HEK293T) and HeLa
cell lines, EdiGene Knockout (KO) Cell Lysates have been optimized through the use of genome editing technology and validated at the genomic level through PCR and Sanger - sequencing techniques to ensure the accuracy and knockout of the target g
cell lines, EdiGene Knockout (KO)
Cell Lysates have been optimized through the use of genome editing technology and validated at the genomic level through PCR and Sanger - sequencing techniques to ensure the accuracy and knockout of the target g
Cell Lysates have been optimized through the use of genome editing technology and validated at the genomic level through PCR and Sanger - sequencing techniques to ensure the accuracy and knockout of the target gene.
Further testing of this culture method on
kidney progenitor
cells derived from human iPS
cells resulted in four times the total amount of
cells over 8 days.
To study the molecular mechanisms of
kidney fibrosis, focusing on
cell - matrix interactions and arachidonic acid -
derived eicosanoids in
kidney injury.
HuH - 7 (human HCC), HepG2 (human hepatocellular blastoma), 293T (human embryonic
kidney fibroblast), HeLa (human cervical cancer
cells), NIH 3T3 (murine fibroblast), and HCT116 (human colon cancer) and its
derived cell line HCT116 p21 − / − (kindly provided by Dr. B. Vogelstein, Howard Hughes Medical Institute, Chevy Chase and the Sydney Kimmel Comprehensive Cancer Center of the Johns Hopkins University School of Medicine, Baltimore, MD; ref.
ViaCyte, Inc. (CA, USA) has received a Small Business Innovative Research Phase III award from the National Institute of Diabetes and Digestive and
Kidney Diseases (NIDDK; MD, USA) to further the development of stem
cell -
derived functional human beta
cells in vitro.
«The development of a functional human
kidney glomerulus chip opens up an entirely new experimental path to investigate
kidney biology, carry out highly personalized modeling of
kidney diseases and drug toxicities, and the stem
cell -
derived kidney podocytes we developed could even offer a new injectable
cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.
Colorado State University had a pilot program using feline fat (adipose -
derived MSCs) as a source of stem
cells (mesenchymal stem
cells = adipose -
derived MSCs) in hopes that introducing them into cats with renal (
kidney) disease would halt or slow the disease.