«The blood - brain barrier forms pretty early in gestation, so the thyroid hormone, even from the mother, is probably not getting through the barrier and into the brain, likely leading to developmental deficits,» says Shusta, whose group was among the first to develop blood - brain barriers from patient -
derived stem cells in the lab dish.
Not exact matches
For example, animal studies have shown that neurons
derived in the
lab from human embryonic
stem cells improve Parkinson's symptoms; however, any residual
stem cells associated with those neurons could form masses of unwanted
cells.
The disease model, described
in a new study by a UC San Francisco - led team, involves taking skin
cells from patients with the bone disease, reprogramming them
in a
lab dish to their embryonic state, and
deriving stem cells from them.
«There have been previous reports of other
labs deriving beta
cell types from
stem cells, no other group has produced mature beta
cells as suitable for use
in patients,» he said.
«
Lab - grown human colons change study of GI disease:
Stem cell derived organoids fill gap
in modeling common ailments.»
The Zeng
lab is making great progress on developing a
stem cell -
derived treatment for Parkinson's disease for testing
in humans.
The
cells,
derived from iPS
cells, RPE
stem cells, or human embryonic
stem cells, are grown and differentiated
in the
lab, then placed
in a harmless fluid to be injected.
Neural
stem cells are found
in adult or fetal brain and spinal cord or
derived from embryonic
stem cells, which have the capacity to become any
cell type
in the body, or induced pluripotent
stem (iPS)
cells, tissue - specific
cells that are reprogrammed
in the
lab to behave like embryonic
stem cells.
Mapping the expression profiles of all genes one
cell at a time revealed unexpected heterogeneity
in the
stem cell -
derived lung
cells, and the research team at the CReM used this information to improve the airway
cells engineered
in the
lab.
Once Woolly Mammoth - like traits appear sufficiently
in stem cell derived tissues, the Church
Lab can begin experiments to generate embryos, possibly through
stem cell embryogenesis.
Although anti-abortion groups oppose embryonic
stem cell research because they believe it destroys unborn human life and that it threatens to expand that destruction as
stem cell research grows increasingly beneficial to humans already born and suffering from disease and debilitation, embryonic
stem cells now are reproduced
in labs from
cells derived years ago from originals.