Sentences with phrase «derived tumour cells»
This makes it much easier to find out who they bind to, where they are localised, and what their levels of expression are — all in the patient derived tumour cells.
http://www.cancerresearchuk.org/
To do this, they switched from using dead tumour cell samples to patient - derived tumour cell lines, in which fresh samples of a person's tumour are grafted onto mice and grown to the required volumes.
Not exact matches
Because such cells are derived from adult cells, not pluripotent cells — which have the potential to form a kind of tumour called a teratoma — they might be safer than iPS cells.
«However, many patients do not respond because myeloid derived suppressor cells (MDSCs), a type of inhibitory cell, are present in the tumour microenvironment.»
«Myeloid - derived suppressor cells (MDSCs) produce reactive nitrogen radicals that alter the receptors on the surface of the tumour to hide it from cytotoxic lymphocytes that kill tumour cells.
The real test will be to inject these cells into mice and see if they form teratomas — tumours containing tissue or structures derived from all three germ layers.
In lab experiments, the research team used cell lines derived from 40 patient tumour samples to identify that CD151 contributes to the survival of cells of high - grade serous ovarian cancer origin.
They turned to cultured cells derived from human lung tumours.
Directly derived from patient tumours without any genetic manipulation, these new products provide the assurance of primary cells with long - term reproducibility and scalability
Although these processes are affected by many different cell types within the tumour stroma, macrophages and other myeloid - derived cells are among the most important players.
Expression of oncogenic β - catenin in Sox2 + young adult pituitary stem cells leads to formation of clusters of stem cells and induction of tumours resembling human adamantinomatous craniopharyngioma (ACP), derived from Sox2 - cells in a paracrine manner.
Within the scope of personalized medicine, this technology presents immense possibilities for testing patient - derived multicellular tumour spheroids / organoids (comprising cancer cells, stromal cells, cancer stem cells and / or immune cells) for disease / biomarker - oriented drug activity and profiling using single - and pair-wise standard / targeted drug combinations.