Sentences with phrase «described human antibody»

Using standard enzyme - linked immunosorbent assays (ELISA) and peripheral blood mononuclear cell (PBMC) assays, researchers discovered that unlike previously described human antibodies to lipids, WR321 did not react with any of 17 other lipids it was tested against, including cholesterol, glycolipids, and other phospholipids such as cardiolipin and phosphatidylserine, but it bound specifically only to two phosphoinositides.

Not exact matches

A physician and cell biologist who won a 1972 Nobel Prize for his work describing the structure of antibodies, Edelman is now obsessed with the enigma of human consciousness — except that he does not see it as an enigma.

The residues altered were selected based on the observation that the three VHH described herein, B9, A14 and B21, bind to the RSC3 probe that was used to isolate the VRC01 - class of human CD4 binding site broadly neutralizing antibodies (Fig. 2) and that previously the introduction of an aromatic residue into the VRC01 - like antibody NIH45 - 46 resulted in increased breadth and potency [38].

Dr. Caskey and her team describe the first in human, phase 1 clinical trial of a first in class fully human highly neutralizing anti-HIV monoclonal antibody.

Normal human lung fibroblasts (NHLF) cells grown in 384 - well Optilux plates were treated with candidate compounds and incubated for 18 hours prior to fixation and staining with Hoescht dye and anti-HMOX1 antibody as described in Materials and Methods.