Here we will go through the basics of how to use CRISPR / Cas to
design research models with different types of targeted mutations.
Not exact matches
I'm at a
research outpost of Volkswagen, the 77 - year - old German car company, and the iPhone on which Loumidi has just snapped our selfie is mounted to the dashboard of an «iBeetle,» a new VW
model that was
designed in collaboration with Apple.
June 15, 2015: Based on the latest
research methodologies, the
models in the Barra U.S. Total Market Equity
Model suite are
designed to provide insight across the investment process, ranging from portfolio construction and risk monitoring to trading.
CXOadvisory.com presents financial markets
models,
research summaries, analyses and reviews
designed for objective, unique and concise value to serious investors, financial advisors and money managers — a modicum of actionable conclusions filtered from a very noisy environment.
Schleiermacher
designed that
model precisely to unite a
research university's wissenchaftlich education with education for one of society's «necessary» professions.
Those of us who have been involved in
designing and promoting various
models for the process of sustained prophetic inquiry can testify to the general lack of interest of ecclesial bodies in such ministry: «social action» is by and large out, and, where it is a priority among church leaders, most of its practitioners are concerned with direct action, not action
research.
Those enhanced resources include a contemporary video conferencing system that allows customers and manufacturers to be directly involved in the creative process, fully integrated on site marketing
research and testing facilities to gather pre-launch consumer insights and feedback and upgraded
design hardware and software for enhanced
modeling capabilities.
We believe that the programs we have carefully
designed through extensive
research, both in education
models as well as mechanical techniques, are the best available.
Based on the book Attached at the Heart, the Attached at the Heart Parenting Educator (AHPE) program is grounded in attachment theory, informed by cutting edge
research, and
designed as a prevention
model to help parents better understand and apply the Eight Principles of Parenting for a child's optimal physical and emotional development.
Jane Sandall was and is principal investigator for two studies evaluating
models of midwife - led continuity of care (Sandall 2001), and co-investigator on the «Birthplace in England
Research Programme», an integrated programme of research designed to compare outcomes of births for women planned at home, in different types of midwifery units, and in hospital units with obstetric s
Research Programme», an integrated programme of
research designed to compare outcomes of births for women planned at home, in different types of midwifery units, and in hospital units with obstetric s
research designed to compare outcomes of births for women planned at home, in different types of midwifery units, and in hospital units with obstetric services.
Whoever
designed the new 2017
model obviously did zero market
research here.
From our
research, we've learned about numerous
models available, from pared down
designs to styles with all the bells and whistles.
The strongest
research methods for psychological studies are: qualitative findings versus quantitative; experimental rather than descriptive or correlational; controlled - experiment, meta - analysis, and observation
designs over archival, case study, computational
modeling, content analysis, field experiment, interview, neuroimaging, quasi experiment, self - report inventory, random sample survey, or twin study; and prospective (where subjects are recruited prior to the proposed independent effects being administered) and longitudinal (where subjects are studied at multiple time points) rather than retrospective or cross-section study.
I've heard from folks like the experts at Baby Bargains that newer
designs don't have this problem as much, but
researching a
model's particular security issues is a must.
Declan Devane is a co-author in one of the included trials in this review (Begley 2011) Jane Sandall was and is principal investigator for two studies evaluating
models of midwife - led continuity of care (Sandall 2001), and co-investigator on the «Birthplace in England
Research Programme», an integrated programme of research designed to compare outcomes of births for women planned at home, in different types of midwifery units, and in hospital units with obstetric s
Research Programme», an integrated programme of
research designed to compare outcomes of births for women planned at home, in different types of midwifery units, and in hospital units with obstetric s
research designed to compare outcomes of births for women planned at home, in different types of midwifery units, and in hospital units with obstetric services.
The findings are valuable for language teachers, and the
research design is likely to serve as a
model for many future SFL studies.»
Researchers with the Air Transportation Center of Excellence for Airline Cabin Environment
Research are testing a system that uses mathematical
models and sensors
designed to pinpoint problem passengers down to their seat number and alert flight and ground crews of an emergency.
To address the complexity of the biologic pathways that create and respond to pressure sore development, the researchers
designed a computational, or «in silico,»
model of the process based on serial photographs of developing ulcers from spinal cord - injured patients enrolled in studies at Pitt's Rehabilitation Engineering
Research Center on Spinal Cord Injury.
In
Design for the Environment: Life - Cycle Approach Using a Newsvendor
Model, University of Virginia Darden School of Business Professor Gal Raz and
research colleagues investigated which segments of a product's life cycle create the biggest environmental impacts and where firms should invest their resources in order to reduce those impacts.
Huang led the portion of the
research focused on theory,
design and
modeling.
► In this week's STM, the American Asthma Foundation's (AAF's) William Seaman, Richard M. Locksley, and Michael J. Welsh «describe a grant program
designed by the... (AAF) that taps talent from diverse pools of investigators — a
model that might spur innovation in other
research realms.»
To test this theory, the
research team
designed an experiment to see if increased LPA signaling led to schizophrenia - like symptoms in animal
models.
He sees the capability of using the team's
research in the future to
design models that will help game managers, conservation managers, farmers and tour operators predict animal migration, whether it's zebras or other migratory animals.
His multidisciplinary academic
research spans computer
modeling, protein - protein / protein - ligand structural analyses, drug
design, and synthetic medicinal chemistry, incorporating the principles of chemogenomics.
In 1991, Brook Hansen, a Huddersfield - based motor manufacturer, and Orb Electrical Steels of Newport, Gwent, convinced the EEO to fund
research aimed at
designing high - efficiency motors that cost the same as standard
models.
The computer
model,
designed by
research fellow Iain Couzin, could lead to improved guidance systems for clusters of robots, such as those used to gather oceanographic and atmospheric data.
It will provide researchers with a level of detail not typically found in academic
research papers, including 3D
models, bills of materials, raw experimental data, multimedia step - by - step tutorials, and case studies of various soft robot
designs.
Another experiment, one
designed by students, will observe fruit flies as a
research model for learning how diseases work at the cellular and molecular levels.
Now,
research by a University of Huddersfield scientist has led to the development of mathematical
models that can ensure new pipeline systems are
designed to be as economic and efficient as possible.
Turbine
research — involves
research to improve turbine
design (aerodynamics), understanding the nature of wind (inflow and turbulence), and using computer
models to
design efficient and low - cost turbines (
modeling structures and dynamics).
The MD / PhD program at UT Houston and the Anderson Cancer Center was
designed to train investigators who could better bridge the gap between basic science and clinical
research, and as an alternative to the traditional MSTP program
model.
Michael Keane, Process Development Director, Boston Scientific Clonmel, commented: «The relationship with MCCI has enabled a unique and accessible
model of access to leading circuits
design research, talented researchers and a flexible, business - like IP
model.
Cancer
Research UK - funded scientists have designed a computer model that applies techniques used to analyse social networks to identify new ways of treating cancer, according to research published in PLOS Computational
Research UK - funded scientists have
designed a computer
model that applies techniques used to analyse social networks to identify new ways of treating cancer, according to
research published in PLOS Computational
research published in PLOS Computational Biology
«In contrast to previous
research, which has shown that consumers prefer a more prototypical car, our study highlights the advantage of introducing some level of freshness into a new
model, particularly if those unique
design elements mimic those of a luxury car,» Balachander said.
In the Coast Guard's spring tests, small - scale
models navigated an ice sheet as long as one - and - a-half Olympic - sized swimming pools at the National
Research Council's ice - tank test facility in Newfoundland to measure various
designs» resistance, power and maneuverability (shown below).
TSRI
Research Associate Giordano de Guglielmo, who was the study's first author, spearheaded the experiment in rat
models of alcohol dependence, which were
designed to express a special protein to distinguish only the neurons activated by alcohol.
The next steps for the
research group are to use what they have learned from this zebrafish
model of gut inflammation to
design better probiotics to treat intestinal inflammation.
In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps
Research Institute (TSRI) have for the first time
designed a drug candidate that decreases the growth of tumor cells in animal
models in one of the hardest to treat cancers — triple negative breast cancer.
Major advances in computational
design, physical
modeling and rapid manufacturing have enabled the fabrication of objects with customized physical properties — such as tailored sneakers, complex prosthetics, and soft robots — while computer graphics
research has seen rapid improvements and efficiencies in creating compelling animations of physics for games, virtual reality and film.
They are collecting data from their numerical
modeling and experimental
research to benefit wave energy technology with improved methodologies, strategic control systems
design and testing practices for wave energy converters.
Expertise to
design and produce genetically engineered mouse
models for use in biological and biomedical
research.
His
research combines laboratory experiments and mathematical
models to more fully understand how head and neck cancers form and how to better
design treatments for these cancers.
As an example of how practical and basic
research can work together, Moss described work in the U.S. involving water utilities, university scientists, and private firms to pilot use of climate
models and water utility
modeling to
design resilient water systems.
While at NIMBioS, Agusto's
research agenda includes
designing an optimal control
model for the malaria vaccine.
In fact, the JP and its collection of sensors and custom -
designed models has placed Lake George under a level of
research supervision unlike anything else.
The Center for Predictive Medicine recognizes the challenges of translational
research such as in
designing and implementing high - throughput screens and assessing small molecules and potential vaccines for their efficacy in small animal
models of disease.
Two grants: $ 700,000 (3 years); $ 750,000 (3 years) «Computational
Research & Development for Rapid Sequencing Nanotechnology» «Experimental
Research & Development for Rapid Sequencing Nanotechnology» This group will develop computational
modeling to guide the fabrication of a novel nanotechnology sequencing device, as well as
design electronic control and detection experiments.
He hopes his
research will provide a framework for
designing and implementing effective malaria control strategies and a new approach for
modeling indirectly transmitted diseases.
A range of
research interests are possible within the themes of bioinspired robotics and medical device
design; however, it is expected that mechanical
design, robot control, biomechanical
modeling of biological systems, mechanism
design and kinematic analysis, device characterization and optimization, bioengineering as well as experimental / analytical mechanics will be key features of the
research.
Enriched by the rapid evolution of these technologies, TEFOR - TACGene has developed a solid expertise in the
design, production and use of TALE - N and CRISPR / Cas9 systems, both for its own
research projects in cultured cells and in collaboration, in many
model organisms, including the rat, zebrafish, Drosophila, and Xenopus as part of the National Infrastructure in Biology and Health TEFOR supported by Investissement d'Avenir programme (2012 - 2019).