Sentences with phrase «designing synthetic proteins»

By designing synthetic proteins that can only interact with a pre-determined partner, and introducing them into cells, the team revealed a key interaction that regulates the ability of embryonic stem cells to change into other cell types.

«We can now design synthetic proteins that are far more sophisticated than natural ones, and use such super-performance proteins toward advancing science and medicine,» he said.

Not exact matches

The key technological innovation that enabled this achievement was the use of monobodies - small, synthetic proteins that can be custom - designed to bind to highly specific locations on target proteins.

Researchers hoping to design new materials for energy uses have developed a system to make synthetic polymers — some would say plastics — with the versatility of nature's own polymers, the ubiquitous proteins.

His multidisciplinary academic research spans computer modeling, protein - protein / protein - ligand structural analyses, drug design, and synthetic medicinal chemistry, incorporating the principles of chemogenomics.

With the help of the Mira supercomputer, located at the Argonne Leadership Computing Facility at the U.S. Department of Energy's (DOE) Argonne National Laboratory, the scientists have successfully designed and verified stable versions of synthetic peptides, components that join together to form proteins.

The researchers then designed synthetic versions of Grb2 that could only interact with one protein from a pool of dozens that normal Grb2 is known to network with.

«Niederberger and colleagues have designed a new kind of allergy vaccine which consists of synthetic fragments of allergen proteins, instead of natural extracts of allergen that have been the mainstay of allergy vaccines for over 100 years.

POL6326 is designed through protein epitope mimetic (PEM) approach, where epitope from a recombinant protein is transferred to a synthetic scaffold [120].

This joint venture, funded by the European Research Council, EPSRC and NPL's Strategic Research Programme, is a rare blend of interdisciplinary research bringing together expertise in robotics, haptics and machine vision with synthetic and cell biology, protein design, and super - and high - resolution microscopy.

Our Small Bites are designed for dogs < 30 lbs 90 Count Small Bites - Per Soft Chew Methylsulfonylmethane (MSM) 300 mg Glucosamine HCI (Synthetic Source) 160 mg Omega 3 (Flaxseed Oil) 160 mg A Proprietary Blend of (Blue Green Algae Extract, Citrus Bioflavonoids, Calcium Phosphate, Manganese Sulfate, Ascorbic Acid (Vitamin C), Zinc Sulfate, Alpha Lipoic Acid and Grape Seed Extract) 100 mg Creatine Monohydrate 100 mg Turmeric 15 mg Eicosapentaenoic Acid (EPA) 3 mg Docosahexaenoic Acid (DHA) 2 mg Boron 30 mcg Selenium 3 mcg Alpha Tocopherol (Vitamin E) 8 IU Inactive Ingredients: Hydrolyzed Vegetable Protein, Magnesium Stearate, Marine Lipid Concentrates, Natural Liver Flavor, Sucrose.

Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign