Smaller «between» cells
called desmosomes join adjacent cells together to form a strong, sturdy structure, which prevents large molecules from passing through.
SV = Secretory vesicle; RER = Rough endoplasmic reticulum; BM = Basement membrane; MFG = Milk fat globule; CLD = Cytoplasmic lipid droplet; N = Nucleus; PC = Plasma cell; FDA = Fat - depleted adipocyte; TJ = Tight junction; GJ = Gap junction; D
= Desmosome; ME = Myoepithelial cell.
When your stratum corneum loses moisture, when TEWL increases, enzyme production is inhibited and
desmosome activity remains stubbornly high.
Every skin cell in your face is bound to your skin by proteins
named desmosomes.
It's unnecessary for dry and dead skin cells to remain on your skin, and therefore, your living skin cells produce several enzymes which
degrade desmosomes, allowing the shedding of dead skin cells (technical name: desquamation).
The other cellular junctions are called Gap junctions, adherens junctions and
desmosome junctions.
Indicated are apical microvilli (AMv), melanin - containing melanosomes (red arrows), the basal nucleus (N),
desmosomes (white arrows) and basal lamina (black arrows).
If inflammation is present it will weaken the structure of
the desmosomes and larger molecules can escape through.