Sentences with phrase «destroy hypocretin»

That knowledge, coupled with evidence that narcolepsy in humans might be an autoimmune disorder, has led many researchers to suspect that sufferers have immune systems that are genetically predisposed to attack and destroy hypocretin - producing cells.

In patients with narcolepsy, their immune system destroys the hypocretin cells located in the brain, which are important in order for them to stay awake.

Not exact matches

The result indicates that T cells and HLA, which together regulate much of the body's immune response, gang up in a unique way to destroy narcoleptics» hypocretin cells, the team reports online this week in Nature Genetics.

Symptoms appear only after more than 90 % of the hypocretin - producing neurons have been destroyed.