Not exact matches
«Proper blood
cell production is dependent on functioning hematopoietic stem and progenitor
cells that are
destroyed during conditioning procedures for transplantation or following
bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies
in cellular and molecular physiology at the Sackler School.
In acute myeloid leukemia, undifferentiated bone marrow cells grow uncontrollably in the blood and bone marrow, crowding out and destroying healthy cell
In acute myeloid leukemia, undifferentiated
bone marrow cells grow uncontrollably
in the blood and bone marrow, crowding out and destroying healthy cell
in the blood and
bone marrow, crowding out and
destroying healthy
cells.
«
Cells in the
bone marrow are probably being
destroyed,» he says.
When BubR1H / H; INK - ATTAC mouse
bone marrow cells were pushed into senescence
in vitro by the PPAR - γ - activating drug rosiglitazone, a subpopulation of the
cells exhibited high levels of INK - ATTAC expression and GFP, coupled with SAβ - gal staining; subsequent to treatment with the INK - ATTAC activating drug, these
cells rapidly entered into apoptosis, and within 48 h were either
destroyed or
in the
cell death process.
A patient receives intensive chemotherapy with or without total body irradiation therapy
in an attempt to kill all cancerous
cells, but which also
destroy his / her own
bone marrow function.
In other cases, people who have had had high doses of radiation or chemotherapy to
destroy life - threatening cancer
cells, the treatment can stop their
bone marrow's ability to make blood
cells.
In older adult pets, diseases of the immune system and
bone marrow that cause blood loss due to loss of clotting ability (thrombocytopenias),
destroy red blood
cells directly (autoimmune hemolytic anemias) or prevent their formation (aplastic anemias) are a less common but significant cause.
The
bone marrow, which produces blood
cells, is also
destroyed, resulting
in anemia.
Parvovirus attacks
cells that divide rapidly
in the body can rapidly
destroys vital
cells such as
bone marrow and white blood
cells.
Feline Panleukopenia Virus (FPV), after entering into the body,
destroys dividing
cells in the
bone marrow, lymph tissues, epithelium (outer layer) of the intestine etc, thus severely depriving the immune system of the body.