Because the combination
destroys other tumors besides the injected one, it might eliminate metastases, or the secondary tumors that result when cancer spreads, he says.
Not exact matches
Metastasis, or cancer spread by the formation of
tumors at new sites, is generally what makes cancers deadly because surgery and
other treatments are unlikely to find and
destroy every cancer cell.
They have detected, for example, revved up signaling molecules involved in inflammation, such as
tumor necrosis factor α (TNFα) and
other cytokines; skewed populations of natural killer cells and
other immune cells; imbalances in the protein -
destroying enzymes called proteases; and a shortening of the telomeres, the «end caps» on chromosomes, which indicates prematurely aged cells.
Built on an easy - to - make polymer, these particles can be used as contrast agents to light up
tumors for MRI and PET scans or deliver chemo and
other therapies to
destroy tumors.
In cancer, Tregs are recruited by
tumors and prevent
other types of T cells, including cytotoxic T cells (also called CD8 cells) from attacking and
destroying cancer cells.
The virus is engineered to grow in cancer cells,
destroy these
tumors, and then spread to
other cancer sites.
The mutations may be in genes governing some aspect of the immune system but they might also be in
tumor suppressor genes whose job it is to seek out and
destroy cancerous cells, genes that control cell division, genes that control normal cell death, and
other types as well.