The researchers behind the new study were particularly interested in the timing of the transition
from destructive inflammation to constructive, healing inflammation.
Once in your brain, your stem cells are called upon to perform the important task of improving blood flow to tissues,
halting destructive inflammation and premature tissue death, while ultimately replacing damaged cells.
Hakonarson hopes that his team's discovery will lead to better therapies by designing small molecules to bind this receptor — thereby reducing
the destructive inflammation.
JAKs carry signals from various inflammatory messenger substances, such as interleukin - 6 or interferons, into the cell and are therefore largely responsible for triggering
the destructive inflammation that occurs in rheumatoid arthritis.
An experimental compound appears to improve stroke outcome by reducing
the destructive inflammation that can continue months after a stroke, scientists report.
A daily dose of a common substance may help reduce
the destructive inflammation of autoimmune diseases like rheumatoid arthritis, scientists say.