While our analysis does not provide any
details about how the computationally re-designed receptor binds the TNT ligand in planta, we consistently see reproducible
signal transduction in our in vivo systems (bacterial and plant).
The Reactome Knowledgebase (https://reactome.org) provides molecular
details of
signal transduction, transport, DNA replication, metabolism, and other cellular processes as an ordered network of molecular transformations - an extended version of a classic metabolic map, in a single consistent data model.