Research also needs to adequately control for covariates that may confound the effects of PAE, such as family processes (eg, problematic parenting or family conflict) and parental characteristics, especially maternal substance use.1, 12 Researchers also need to account for genetic liabilities that are shared by parents and offspring.13, 14 A woman's genetic risk of substance use could be passed down to her children and subsequently affect their behavior.15 Research on the consequences of PAE, therefore, needs studies with large samples, with sufficient statistical power to
detect small effects, using analytical methods and designs that can account for potential confounds, including factors that are not measured.
Indeed, we only had adequate statistical power to detect medium and large effects, and were under - powered to
detect small effects.
To
detect small effects (d =.3), power was 52 — 69 % across the peer - report scales, 54 — 65 % across the self - report scales, and 71 — 78 % across the teacher - report scales.
Limitations include concerns regarding sufficient power to
detect small effects and possible bias.
In these patients, it is not possible to determine whether the negative findings were the result of the low «sensitivity» of the method (e.g., failure to
detect small effects), or whether they genuinely reflect the patients» limited cognitive abilities.
«The meta - analytic study requires a certain number of studies (at least 17 - 20 experiments) to
detect smaller effects and to avoid false - positive results (if the findings are driven by the effect of single experiments),» Zinchenko said.
Even though the trial was powered to
detect a small effect size, only modest improvements in parenting risks were found, but no impact on child behavior at follow - up time points of 18, 24, or 36 months was found.
However, the results suggest that contact - only CSA may produce a significant association with parenting stress and that studies including both contact and non-contact CSA may need larger sample sizes to
detect smaller effects.
Not exact matches
A person who subscribes to the AEC philosophy might phrase the
effect of continuing testing upon the incidence of leukemia as follows: «This
effect is so
small that it can not be
detected with certainty in death statistics.
Bigger
effects are easier to
detect than
smaller effects, while large samples offer greater test sensitivity than
small samples.
As our study has a power of 80 % (α = 0.05) to
detect a difference of at least 5.7 points for the Bayley PDI and 2.6 points for the Peabody motor scales, we can not exclude a
small positive
effect of breast feeding on motor development.
Although the number of participants in the study was relatively
small, the researchers report that it was sufficiently large to
detect clinically relevant
effects.
The number of people involved in Kable's study was too
small to
detect any tiny improvements in performance, so it's possible a
small effect was missed.
«We believe that RS - based SNP prioritization may provide guidance for more targeted and powered approach to
detecting the disease - associated SNPs with
small effect size,» he concluded.
This
effect allows researchers to
detect changes in humidity as
small as 0.1 percent.
Take the example of antiretroviral drugs, where you got
small effects with studies of individual drugs compared to two drug therapies that you really could not have
detected without the right kind of study and right kind of statistics.
The frequency doubling
effect is strong enough so that arrays that are too
small to see with the naked eye can be
detected easily.
These assays make it possible to
detect even
small changes in DNA methylation, making them useful in the hunt for new drugs to reverse the
effects of repeat expansion.
Alternatively, micro explosions, termed nanoflares — too
small and frequent to
detect individually, but with a large collective
effect — might release heat into the corona.
More analyses will be needed to
detect risk variants with
smaller effects, or ultra-rare variants.
The sensors
detected changes in oxygen pressure as
small as 15 millimeters of mercury, and it took less than 10 minutes to see the
effects of a change in inhaled gas.
BACKGROUND AND PURPOSE White - matter hyperintensities (WMHs)
detected by magnetic resonance imaging are thought to represent the
effects of cerebral
small - vessel disease and neurodegenerative changes.
This is the deepest large mm - wave dataset in existence and has already led to many groundbreaking science results, including the first galaxy clusters
detected through their Sunyaev - Zel «dovich
effect signature, the most sensitive measurement yet of the
small - scale CMB power spectrum, and the discovery of a population of ultra-bright, high - redshift, star - forming galaxies.
The large number of DNA samples brought together in this study may enable the researchers to
detect genes whose individual
effects in the disorder may be
small but may still play a role.
The
effect is
small since the Earth's mass is
small, so atomic clocks must be used to
detect the difference.
Furthermore, the number of subjects is too
small to
detect an
effect.
This
small effect would add up over time, but it would be difficult to
detect in a research study lasting only weeks and it would take a long time for an individual to see the results.
The associations between high versus low consumption of decaffeinated coffee and lower risk of type 2 diabetes21 and endometrial cancer40 were of a similar magnitude to total or caffeinated coffee, and there was a
small beneficial association between decaffeinated coffee and lung cancer.48 The other outcomes investigated for decaffeinated coffee showed no significant associations, though it should be noted that meta - analyses of consumption would have much lower power to
detect an
effect.
And, second,
smaller districts — where most Americans attend school — do not have a sufficient sample size within their own data to
detect the hoped - for
effects.
Given these
small sample sizes, it takes fairly large preschool
effects for such
effects to be
detected as statistically significant.
But Forbush was handicapped by lack of knowledge about the sub-lethal neurological
effects of pesticides, and by a lack of technology capable of
detecting the very
small amounts of pesticides that can induce neurological harm.
However, the albedo - induced cooling
effect is expected to be
small and was not
detected in observed trends in the study by Matthews et al. (2004).
Paper J notes that the anthropogenic
effect on sea level rise in one region of the world (the Pacific Ocean) over one period of time (1993 - 2013) is too
small to
detect at a statistically significant level due to factors such as: a)
small sample size (only 20 years), b) the
effect of control variables (such as the IPO), c) limitations of satellite altimetry measurement, the technique being used to measure sea level in paper H. Paper K offers a contrasting account of paper J, noting that part of the Pacific sea level rise is anthropogenic.
It was likely that local conditions at scales finer than those
detected by satellite observations increased or decreased the
effect of the thermal stress within and among reefs at the sub-pixel scale (e.g., coral community structure,
small - scale hydrodynamics, past bleaching; the analysis of which were beyond the scope of this study).
The second factor is the insulating
effect of the atmosphere of which well over 90 % results from atmospheric water in the form of clouds and water vapour with the remaining 10 % due primarily from CO2 and ozone with just a slightly detectable
effect from methane and a trivial
effect from all the other gases named in tyhe Kyoto Accord that is so
small it can't even be
detected on measurements of the Earth's radiative spectrum.
If something exists but is too
small to be
detected then it only has an abstract existence; it does not have a discernible existence that has
effects (observation of the
effects would be its detection).
Because our excess heat is concentrated in what amounts to point sources, and those point sources are almost invariably located near to the temperature monitoring sites, you may want be a little kinder to Phillip and his opinion that waste heat accounts for a significant amount of our «warming» unless you have convincing evidence that the heat is dissipated so rapidly that its net
effect is
smaller than our ability to
detect.
So, if there was any
effect by the steam release just days earlier, it appears to be so
small as to be impossible to
detect.
MWMT and MAP had relatively
small effects on tree growth (less than 40 % of the analyzed groups showed significant correlations), whereas the
effect of MCMT on tree growth was mostly negative among the
detected significant groups (Fig. 3B).
You also say that the GH
effect is too
small to be
detected from individual station records.
Claims that even a seasonal signal has been
detected, let alone a synoptic scale signal, would be grossly premature — indeed, I doubt that anything other than a huge
effect would be detectable in such a
small time period — and there is no indication of that at all.
A priori power analyses determined that a total of 234 participants would offer 80 % power to
detect a
small - to - moderate
effect size.
This is not such a great limitation for many psychological and psychiatric phenotypes with substantial heritabilities of around 0.5, but may cause problems in
detecting smaller, yet potentially important genetic
effects.
Power calculations also showed that the trial had adequate power to
detect effect sizes in the
small to moderate range.
This suggests that the study had adequate power to
detect effect sizes in the
small / moderate range.
None of the trials in the 3 meta - analyses had enough power to
detect effect sizes
smaller than d = 0.34, but some came close to the threshold for
detecting a clinically relevant
effect size of d = 0.24.
Generally, larger studies have more power to
detect significant
effects compared with
small studies.
Fourth, although post-hoc power analyses showed that this study with about 50 ICP / partner dyads had more than 90 % power to
detect large
effects (r > 0.50), it had less than 60 % power to
detect small to medium
effects (r < 0.30), making it possible to miss
effects.
Thus, we developed longer versions for
smaller studies in which this might serve as a primary outcome measure - providing the highest precision and power for
detecting effects.
It's also an appropriate design for studies with
small sample sizes that may not have the desired power for the statistical analysis to
detect an
effect when there is one.