Budimirovic says the current study updated the 2013 recommendations by using a more
systematic approach that classified existing outcome measures as either being able to
detect shorter - term
changes (measures in FXS placebo - controlled trials lasting less than 12 months) or longer - term
changes (lasting longer than 12 months)
changes and by grading the measures» quantitative properties using the COnsensus - based Standards for the selection of health Measurement Instruments (COSMIN) system, an initiative that aims to improve how health measurement tools are selected.
These results demonstrate the value of a
systematic investigation of bacterial protein
changes in identifying proteins of likely importance in
detecting bacterial pathogens and developing effective vaccines.