A prospective, controlled study of the effect of breast milk on infection among low birth weight infants was conducted in India in 1981.18 Although the sample size was small, 62 infants, the study design was a randomized block design in which feeding schedules for breast milk or formula were randomly allocated within
groups of infants that were
determined to be relatively
homogeneous with respect to factors predisposing to infection.
Also, it is suggested that one
determine if the activity should be done in cooperative learning
groups, and if it is, then the number of students in each
group and whether they should be heterogeneous or
homogeneous.