Labs are now able to analyze stools and
determine microbiome composition.
However, the Weizmann researchers were surprised to discover that the host's genetics play a very minor role in
determining microbiome composition — only accounting for about 2 % of the variation between populations.
Not exact matches
Both studies demonstrate that the
composition of the gut
microbiome — the swarms of microorganisms naturally dwelling in the intestines —
determines how effective these cancer immunotherapies are.
«If testosterone drives the microbial
composition of the gut, a compelling next step would be to
determine if treatment of PCOS with testosterone blockers or oral contraceptives results in the recovery of the gut
microbiome,» said Thackray.
While genetic and epigenetic factors play between the host organism and the microbiota —
determining which microbes successfully colonize the gut and other organs — the ultimate dictating force of the
composition of an organism's
microbiome is diet and environment.