So, rather than the number of AMPA receptors themselves, the abundance of scaffolding proteins appears to
determine synaptic strength, effectively allowing AMPA receptors to receive signals from glutamate.
Researchers have observed AMPA traveling from the inside of a neuron to the downstream end of a synapse, but they remain uncertain as to whether the migration into and out of the synapse is the major component in
determining synaptic strength.
Not exact matches
His lab is building detailed computer models of synapses and the networks they sustain in order to
determine how they collect firing statistics during wakefulness and sleep and when they change
synaptic strengths to reflect the difference.