MS / MS refers to a newer technique called tandem mass spectrometry, an even more powerful method of
determining chemical structures.
Van der Donk asked Drennan, an expert in
determining chemical structures of proteins, if she could try to reveal the structure of MPnS, in hopes that it would help them find more variants of the enzyme in other bacteria.
To find out, Engler and her colleagues extracted cyanogens from the plants and recently emerged butterflies and
determined their chemical structures using nuclear magnetic resonance and mass spectroscopy.
Not exact matches
This testing
determines how your product interacts with various flexible packaging
structures, and will help with identifying adverse effects that a product has on flexible packaging materials, such as
chemical degradation or delamination.
She
determined the structural difference between pepsin and its precursor pepsinogen, analyzed the proteins» shapes, and
determined how temperature and
chemical conditions influence their
structures.
X-ray crystallography (a technique used for
determining the atomic and molecular
structure of a crystal, in this case, a Gamillus crystal) and point mutagenesis suggest the acid tolerance of Gamillus is attributed to stabilization of deprotonation in its
chemical structure.
Physics and chemistry professor Ahmed Zewail and his colleagues at the California Institute of Technology married two previously independent lines of research: femtochemistry, in which pairs of brief laser pulses initiate and monitor a
chemical reaction, and electron diffraction, in which a molecule's
structure is
determined from the scatter of electrons fired at a crystal containing billions of copies of that molecule.
In addition, terahertz radiation could
determine the
structures of many complex
chemicals, yet is safe for biological use — desirable properties for medical imaging.
When the sample produced a
chemical compound they were not able to identify, the researchers tried high - resolution mass spectrometry to
determine the
chemical compound's components but were unable to figure out its exact molecular
structure.
Washing the leaves in a variety of
chemical baths helped Elliott
determine the leaves»
structure and species.
They found that the ELVOC formation happens very fast and that the
chemical structure of the precursor gases
determines how effectively they form ELVOC's.
By comparing high - resolution
structures of two complexes — one containing both a DUB and a pseudo-DUB, and two copies of an inactive DUB by itself — the team
determined that KIAA0157 alters the shape of the BRCC36 active site, by swinging an amino acid into position to make the complex able to catalyze
chemical reactions.
In this test participants were challenged to predict nine recently
determined crystal
structures of five target compounds given only the
chemical diagram of the molecules and conditions of crystallisation, with two sets of predictions allowed per target compound.
Chemists immediately wanted to
determine its
chemical formula and
structure.
The samples ranged from a simple alcohol to a complex plant hormone, and the new method, dubbed «CAL» for covalent alignment (the molecules form a type of
chemical bond known as a covalent bond in the MOFs), enables researchers to
determine the complete
structure of a molecule from a single MOF crystal that contains the sample molecules in its pores.
At the SGC, the fellows will carry out
chemical assays or
determining the co-crystal
structures of their molecules with their protein targets, and in industry the fellows will design, synthesize and characterize the
chemical probes.
HPP - 4382 does not have electrophilic properties, as
determined by its
structure and lack of
chemical reactivity with common thiol - containing compounds such as N - acetylcysteine.
In addition to extending a relatively new method of
determining the
chemical composition of planets to examine their internal
structure, the team found that the rocky material being accreted by the star could be comprised of minerals that are typically associated with marine life processes here on Earth.
Utilizing this
structure, we searched
chemical databases for scaffolds exerting significant binding interactions similar to (or stronger than) those exerted by ponatinib,
determined by comparing their free energies when docked inside of the RIPK2 binding site.
Other major projects include systematic identification of biomarkers to improve clinical management of cardiotoxicity induced by cancer therapies, identification of ectopic pregnancy biomarkers, and use of
chemical crosslinking coupled with high resolution mass spectrometry and molecular modeling to
determine structures and dynamics of large protein complexes.
The laboratory is also using
chemical crosslinking - based structural mass spectrometry techniques coupled with molecular modeling to
determine structures of large protein complexes and characterize protein conformational changes involved with physiological processes.
The group, led by principal investigator and Ames Laboratory scientist Emily Smith, is receiving $ 1 million a year for three years from the DOE's Office of Science to develop a subdiffraction Raman imaging platform that will provide an unprecedented look at the specific
chemical structures of plant cell walls and then
determine how best to deconstruct plant material as a source of biofuels.
Antibiotics vary with their
chemical structure, and this will
determine what type of infections they treat, and whether they kill the bacteria (bactericidal) or simply slow bacterial growth to let the immune system defeat the infection (bacteriostatic).
Epic Pharma, LLC, Laurelton • NY 2008 — 2010 Chemist Analyzed products with organic and inorganic compounds to
determine chemical and physical properties, composition,
structure, relationships, and reactions utilizing chromatography HPLC, spectroscopy, and spectrophotometer techniques.