Sentences with phrase «develop cystic fibrosis»

Although millions of people carry the CF gene, only people who inherit a copy from each of their parents will actually go on to develop cystic fibrosis.

«We know that it is more likely for people in certain parts of Northern Europe to develop cystic fibrosis,» said Jablonski.

Not exact matches

Galapagos (GLPG)- Partnered assets continue to progress in the clinic, its IPF program offers optionality, efforts in cystic fibrosis to develop a triple combination therapy should not be underestimated and Gilead (GILD)- partnered filgotinib could have peak sales of over $ 3 billion alone.

Prior to insemination, a woman and man will both undergo genetic testing to determine whether or not their baby will develop a genetic disease like cystic fibrosis, sickle cell, or Huntington's disease.

Additional reasons for deciding not to breastfeed can include concern about the quality and quantity of breast milk, and partner and family support, which are common across developed and developing countries.10, 11 Women who decide not to breastfeed are also more likely to have smoked during their pregnancy, be primiparous mothers (i.e., having their first child), and to have a child born low birth weight or with complex health issues such as cystic fibrosis.9, 12 Prenatal and post-natal stressful experiences may also reduce the duration of breastfeeding.13 Finally, several studies suggest that mother's who return to work within the first 6 months postpartum or anticipate an early return to full - time employment, are less likely to breastfeed.

Rogers designed a new set of processes and techniques to develop the porcine model of cystic fibrosis, but he soon realized those processes could have a much wider impact.

Like Gilead, which aims to develop treatments for HIV / AIDS, hepatitis B and C, influenza, pulmonary arterial hypertension, and cystic fibrosis, other top employers accentuate the positive aspects of the life science industry by performing their R&D in entirely new areas.

When conventional wisdom said only gene therapy could correct the root cause of cystic fibrosis, Vertex developed pill - based treatments that address the underlying disease mechanism, says Altshuler.

He is head of a team currently developing a similar type of test that identifies Pseudomonas aeruginosa, a bacterium that often causes infections in people with cystic fibrosis.

Despite much effort, no one has managed to develop an effective form of gene therapy to treat the lung problems of people with cystic fibrosis.

Lisa Harris, of Dalton High School in New York City, won this year's top Siemens prize for individuals — a $ 100,000 college scholarship — for developing a new method to detect carriers of a gene responsible for cystic fibrosis.

Those with asthma and cystic fibrosis are at highest risk of developing allergic aspergillosis.

Vice-Chancellor of Queen's University Belfast, Professor Patrick Johnston said: «Although this is good news in one sense, these figures pose a major challenge to healthcare providers in that adult cystic fibrosis services will need to be developed quickly and effectively to meet demand.

Researchers have developed a new approach for growing and studying cells they hope one day will lead to curing lung diseases such as cystic fibrosis through «personalized medicine.»

One of the most dangerous of these bacteria is P. aeruginosa, which, within the unique mucus that forms in the lungs of a person with cystic fibrosis, develops into large, antibiotic - resistant colonies.

Since the discovery of the genetic basis for cystic fibrosis in 1989, scientists have developed a variety of viral and non-viral vector systems for delivering a corrected CFTR gene back into lung cells.

Fast screening — coupled with $ 75 million from the Cystic Fibrosis Foundation — allowed Vertex of Cambridge, Massachusetts, to develop Kalydeco and two other drugs being tested.

Saint: Cystic Fibrosis Foundation Since scientists pinpointed the gene responsible for cystic fibrosis in 1989, the nonprofit group has recruited study participants and donated millions of dollars to develop gene - based treatCystic Fibrosis Foundation Since scientists pinpointed the gene responsible for cystic fibrosis in 1989, the nonprofit group has recruited study participants and donated millions of dollars to develop gene - based treFibrosis Foundation Since scientists pinpointed the gene responsible for cystic fibrosis in 1989, the nonprofit group has recruited study participants and donated millions of dollars to develop gene - based treatcystic fibrosis in 1989, the nonprofit group has recruited study participants and donated millions of dollars to develop gene - based trefibrosis in 1989, the nonprofit group has recruited study participants and donated millions of dollars to develop gene - based treatments.

Most people with cystic fibrosis develop lung infections that involve multiple species of microbes.

The first of many probable applications will likely be the chronic bacterial infections in the lungs of cystic fibrosis patients «that frequently develop resistance to all standard antibiotics, and are the leading cause of death in these patients,» says senior author Ronald Montelaro.

Since the gene behind cystic fibrosis was discovered in 1989, researchers have tried to develop drugs that directly target the faulty protein it makes in those with the disease.

It might be possible, Schonwetter speculates, to develop aerosols containing an LAP - like antiseptic that could be inhaled by cystic fibrosis sufferers to help them fight off lung infections.

We are going to screen a larger library of chemicals to identify molecules that either boost or weaken NMD, which should help develop better and more targeted drugs for treating ALS, muscular dystrophy and cystic fibrosis.»

23andme further offers a report on your genetic health risks, including whether you have genetic mutations for diseases like cystic fibrosis that may affect any future children and how likely you are to develop Parkinson's or Alzheimer's.

Several methodological approaches have been developed for NIPD of cystic fibrosis, which is the most common life shortening, childhood onset autosomal recessive disorder in populations of European descent.

Last month, researchers from the Netherland's Utrecht institute reported in Cell Stem Cell that CRISPR corrected the gene mutation responsible for cystic fibrosis in stem cells developed from two children with the life - threatening disease.

Many of those patients, particularly children and young adults, will develop an allergic reaction to the fungus, Bronchopulmonary Aspergillosis (ABPA), according to the Cystic Fibrosis Foundation.

Using translational research methods, the DZL seeks to jointly develop new approaches for the prevention, diagnosis and therapy of serious lung diseases including asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, diffuse parenchymal lung disease (DPLD), endstage lung disease, lung cancer, pneumonia and acute lung injury, and pulmonary hypertension.

A team of scientists from the UNC School of Medicine and North Carolina State University (NCSU) has developed promising research towards a possible stem cell treatment for several lung conditions, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis — often - fatal conditions that affect tens of millions of Americans.

THE MOUSE MODEL FOR CYSTIC FIBROSIS, as with models for many diseases, owes its existence to a technique called gene targeting, which was developed in the 1980s by Mario Capecchi, a professor of human genetics and biology at the University of Utah who won the 2007 Nobel Prize in Physiology or Medicine for his work.

If you have cystic fibrosis or asthma, you may be more susceptible to developing nasal polyps.

Canadian guidelines for CF clinical care have been developed and are being published by Cystic Fibrosis Canada.

Shorter and specific versions have been developed, such as a 15 - item version for families of children with cystic fibrosis (DeLambo et al., 2004).

Parents raising children with ASD have been found to report higher levels of parenting stress, depression and anxiety, and increased general life stress than parents raising children with Down syndrome (DS), cerebral palsy (CP), fragile X syndrome (FXS), intellectual disability (ID), cystic fibrosis (CF) or typically developing (TD) children [e.g. 11, 12, 13, 14, 15, 16, 17].