There are subjective methods, there are some structural methods, but it's thought that there is a loss of metabolism and function before these occur, so one of the real challenges in the field is to
develop early biomarkers for disease detection and progression.
Not exact matches
Support a multi-year effort led by world - class scientists to
develop a blood test for
earlier detection of breast cancer when survival rates are the highest, known as the EIF Breast Cancer
Biomarker Discovery Project.
The authors anticipate that health care providers will use the
early - detection
biomarkers to test for their presence and levels in blood from pancreatic cancer patients and blood drawn from individuals with a high risk of
developing pancreatic cancer, including those who have a first - degree relative with pancreatic cancer, are genetically predisposed to the disease, or who had a sudden onset of diabetes after the age of 50.
The members of the initiative hope to improve
early detection of cancer by making an impact in a variety of areas, including doing epidemiologic studies on risk factors,
developing new and improved methods of diagnostic imaging, discovering and verifying new
biomarkers as indicators of cancer, and
developing new technologies to aid
early detection.
«If we can find
biomarkers informing us that the most vulnerable parts of the lung have already been infected by RSV, then it could be possible to identify much more quickly the children at more risk for
developing severe lung disease and to get those babies in a treatment protocol at an
earlier time,» Pickles said.
Early attempts to measure
biomarkers or analytes in spit were hampered by inconsistent results and lack of recognized economic benefit to companies
developing immunodiagnostics.
Accordingly, the currently identified miRNA - like fragment may function as an
early biomarker of EVD to advance the diagnosable window and reduce the difficulties in the isolation and treatment of patients who
develop suspicious symptoms.
«This research could help us find
biomarkers for
early detection, as well as provide information for
developing targeted therapies for this devastating disease.»
Future studies will focus on
developing biomarkers capable of making
early predictions on whether patients will
develop a severe form of the disease.
A device
developed to monitor US military pilots looks at
biomarkers in breath to spot the first signs of hypoxia, allowing action to be taken
earlier
Researchers at ETH Zurich have
developed an
early warning system for cancer that grows an artificial mole on your skin when it detects certain
biomarkers (Credit: ETH Zurich)
In addition to her expert skill as a clinician, Dr. Frontera also has many research interests including identifying
biomarkers and predictors of
early brain injury and vasospasm / delayed cerebral ischemia after subarachnoid hemorrhage and their impact on outcome; determining the efficacy of therapeutic strategies and
developing guidelines for the management of patients with intracranial hemorrhage; evaluating the cost, length of stay, quality of life, functional and cognitive outcomes in a broader population of intracranial hemorrhage patients;
developing guidelines for the integration of palliative care into the intensive care unit setting; and evaluating the relationship of Zika virus infection, Guillain - Barre, and other neurologic disorders.
With further research, the team says the concept could be adapted to monitor other
biomarkers besides calcium, to serve as
early warning systems for other gradually -
developing illnesses like neurodegenerative diseases and hormonal disorders.
«Since NEC progresses so rapidly and the symptoms
develop suddenly, a non-invasive
biomarker that allows
early detection of patients at risk is required as a matter of urgency.»
Importantly, the molecular imaging models that are
developed can be employed to accelerate the discovery of targets and drugs for therapeutic intervention, and
biomarkers that could be used for
early diagnosis.
develops biomarkers for
early diagnosis and improved treatment of cancer, with the objective of enabling personalised treatment at an
early stage.
Through powerful and lasting partnerships, the Baruch S. Blumberg Institute seeks to find cures for chronic hepatitis B,
develop early detection
biomarkers for liver disease and liver cancer, train future researchers, nurture biotechnology entrepreneurship, and provide information and support to those affected by chronic hepatitis worldwide.
• the identification and validation of
early biomarkers of autoimmunity and their use to help identifying population at risk of
developing autoimmunity;
A new plasmonic sensor
developed by researchers at the University of Illinois at Urbana - Champaign will serve as a reliable
early detection of
biomarkers for many forms of cancer and eventual... Read more
At present, there is an urgent clinical need to extend our understanding of PD pathology, to
develop novel disease - modifying therapies for PD, and to identify reliable PD
biomarkers to allow for
earlier interventions.
Miller is widely recognized for his research on the impact of toxins in Parkinson's disease (PD) and has created a unique mouse model of the disease to
develop biomarkers of exposure, risk and
early disease.
By
developing biomarkers which are not only sensitive for disease detection but also specific
biomarkers you can solve the problem of both detecting disease
early but also determining the course of treatment in a very specific fashion.
The team will continue to
develop and test an imaging - based
biomarker that can be used in a clinical setting to enable us to understand the molecular changes to the ganglion cells, so we can detect the disease very
early on.
«We can potentially
develop some
biomarkers that allow us to diagnose it
earlier,» MacKenzie said.
A study published
earlier this year in the journal Cancer Epidemiology,
Biomarkers & Prevention linked fish oil supplements to a decreased risk for
developing breast cancer.
We believe that this 10 - lipid phospholipid
biomarker panel reflects the breakdown of neural cell membranes in those individuals destined to
develop advanced moderate cognitive impairment or Alzheimer's disease and may mark the transition between preclinical states where synaptic dysfunction and
early neurodegeneration give rise to subtle cognitive changes.»
Our approach to achieving this goal focuses on three objectives: (1) to
develop a reliable, predictive panel of
biomarkers (including both biological and bio-behavioral measures) that can identify children, youth, and parents showing evidence of toxic stress, and that can be collected in pediatric primary care settings; (2) to conduct basic, animal and human research on critical periods in development and individual differences in stress susceptibility, thereby informing the timing and design of a suite of new interventions that address the roots of stress - related diseases
early in the life cycle; and (3) to build a strong, community - based infrastructure through which scientists, practitioners, parents, and community leaders can apply new scientific insights and innovative measures to the development of more effective interventions in the first three postnatal years.