Sentences with phrase «develop immune signaling»

My group has also shown that lymphocytes from patients with breast cancer, melanoma, and colorectal cancer develop immune signaling defects that blunt their proliferation and function in vivo.

Not exact matches

As many as 20 % of people who develop sepsis will die, not from the infection itself — but from the overload of inflammatory chemical signals created by the immune system which ultimately leads to organ failure.

In some cases, the antibodies that develop to help fight off the bacteria also signal the immune system to attack the body's own cells that bear gangliosides.

That's the promise of a new study, which has found a unique set of signals in the immune cells of people who later developed inflammation, headaches, fevers, and other «adverse events» after receiving a flu shot.

There are antibodies that have been developed now that basically block those inhibitory signals and allow the immune system to act against the cancers.»

Cooke said the team is developing methods to manipulate innate immune signaling of ROS to maximize the production of iPSCs and better direct their differentiation.

Developing strategies to inhibit this signaling within tumor cells could help restore T cell access and enhance the potential of immune - mediated cancer treatment.»

In a paper published online Aug. 31, by Nature Medicine, researchers report that using a monoclonal antibody called anti-CD47, which blocks the «don't - eat - me» signal on malignant cells, to treat mice with an intact immune system provides a much more lifelike way to study and develop an immune - based cancer therapy.