Co-engrafting mice with human tumors that retain the same characteristics and human immune cells, is a new platform to study the relationship between the human immune system and tumors and
develop immuno - oncology - based cancer therapies.
Not exact matches
U.S. health regulators on Tuesday granted accelerated approval for Pfizer Inc's
immuno - oncology drug Bavencio to treat advanced bladder cancer, marking the second approval in less than two months for the treatment
developed along with Germany's Merck KGaA.
The researchers suggest that their blood test serves as a cheap and simple option to pre-select individuals from the general population for further testing by these more invasive and costly methods to exclude the falsely positive subjects.The blood test
developed by Gerwert and colleagues uses a technology called
immuno - infrared sensor to measure distribution of pathological and healthy structures of amyloid - beta.
Alongside his CEO role at Hookipa, Joern is Chairman of Molecular Partners AG and a Board member of Unum Therapeutics, both of which are
developing next - gen
immuno - oncology therapies.
The project associates the expertise of IRIBHM in GPCR discovery and validation, the unique technology on sensory GPCRs
developed by ChemCom, the in - depth tumor immunology expertise of de Duve with the drug discovery capabilities of iTeos and the expertise of ImmunXperts with human primary cells in
immuno - oncology.
This will fast - track new immune - modulating therapies for cancer patients by discovering and
developing small molecule product candidates against
immuno - oncology targets.
iTeos Therapeutics has
developed a novel and potent best - in - class A2A blocker that has been specifically optimized for
immuno - oncology indications to retain a high potency in the adenosine - rich environment found in tumors and to restore cytokine production even in the presence of high concentrations of adenosine.
iTeos has
developed an innovative phenotypic screening platform that is applied to the identification of rational combinations for our current programs, and to the discovery of novel targets for
immuno - oncology.
During the last three years, iTeos has
developed a comprehensive portfolio of
immuno - oncology drug candidates and these additional funds will enhance our capability to demonstrate the potential clinical benefits of our products.
Our
immuno - oncology product candidates are being
developed in two separate approaches: one that targets specific antigens and / or epitopes (such as CMB305 and in our neoantigen collaboration); and an alternative approach that leverages the endogenous antigens found in the tumor microenvironment via intratumoral immunization (such as G100).
Apexigen is a clinical - stage biopharmaceutical company discovering and
developing a new generation of antibody therapeutics for oncology, with an emphasis on new
immuno - oncology agents that could harness the patient's immune system to combat and eradicate cancer.
While our primary focus is on the development of
immuno - oncology therapies, we also establish collaborative partnerships to
develop potential treatments for non-oncology diseases, such as infectious and allergic diseases.
«Our internationally standardized, NGS - based LymphoTrack clonality assays with bioinformatics software provide a comprehensive solution in support of laboratories and pharmaceutical companies
developing new drugs and
immuno - therapies.
Vaccines allow the body to
develop some immunity and ward off the symptoms that are can be life threatening in the less
immuno - competent animals...
CYCLOSPORINE (ATOPICA ®) Cylcosporine is an
immuno - modulating drug originally
developed for use in organ transplant patients but also useful in other immune - mediated diseases.
Andrew Burbidge: We have looked in Australia at biological control of foxes and rabbits and house mice at various times, particularly in the late»80s and»90s, there was work done within CSIRO, funded by the federal government, to see whether you could
develop the idea of
immuno - contraception.
Andrew Burbidge: Yes, I think that having a transmissible virus as the vector for
immuno - contraception or whatever other technique's available is not really a viable option because the feral cat has been bred from the wild cat of Africa, Europe and Asia, and if that transmissible disease, that virus escaped Australia or was taken out purposely by someone who, you know, wanted to cause problems in another country, then we would have actually have
developed a technique for eradicating native animals in other people's countries, and I just think that's not on.
Cyclosporine (Atopica) Cyclosporine is an
immuno - modulating drug originally
developed for use in organ transplant patients but also useful in other immune - mediated diseases.