Furthermore, by combining this information with the characterization of mice genetically engineered to
develop lung tumours, we attempt to elucidate the key genes driving lung cancer initiation, progression and response to therapy.
Not exact matches
Over this time, 30 per cent of the mice
developed tumours around their body, including in their liver, colon,
lungs and spleen.
It recognises the four most common types of cancer — prostate,
lung, colon and breast cancer — at a very early stage, namely when the level of calcium in the blood is elevated due to the
developing tumour.
We have
developed pre-clinical models to identify genes, both in the
tumour cells and in the microenvironment that regulate the spread of cancer to specific organs such as the liver,
lungs and brain.
Her group has
developed pre-clinical models of metastatic disease that are used to identify genes, both in the
tumour cells and in the
tumour micro-environment that regulate the process of metastasis to specific organs such as bone, liver,
lung and brain.
Despite these successes two major problems remain: first, the majority of
lung cancer patients have
tumours without mutations in targetable genes and; second, all patients eventually
develop resistance to treatment with these targeted agents.
Studies have shown that green tea prevents the
developing of many
tumours as a result of carcinogens, primarily breast cancers, skin cancers,
lung cancers, colorectal cancers and oesophageal cancers.
For example dog
tumours rarely
develop in the colon, rectum,
lungs, ovaries or uterus.