Sentences with phrase «develop more tumors»

Chilly mice develop more tumors; gut bacteria aid cancer treatment; two Y chromosome genes sufficient for assisted reproduction; HIV's «invisibility cloak»

Mammals fed a diet of genetically engineered (GE) Roundup Ready corn for two years died earlier and developed more tumors and liver and kidney damage, according to a new study published this week in the peer - reviewed journal, Food and Chemical Toxico

Not exact matches

A new study, conducted by the U.S. National Toxicology Program, found that rats consistently exposed to radiofrequency radiation from cellphones were more likely to develop malignant tumors in the brain and heart.

More than a boon to squeamish students, the see - through frog could aid biologists studying how organs develop and respond to tumors or toxins.

In the presence of these drugs tumors grow faster and develop more extensive networks of the blood vessels they rely on to feed their expansion — a process called angiogenesis, says Jonathan Moss, an anesthesiologist at the University of Chicago (U. of C.) Medical Center.

By releasing the brakes that tumor cells place on the immune system, researchers are developing a new generation of more powerful treatments against malignancy

In some horses, tumors develop as small bumps under the skin or as scaly lesions that easily can be removed by a veterinarian, but in other horses the problem becomes much more serious.

The researchers «deserve a lot of credit» for testing the approach in the mice that spontaneously develop breast tumors, he says, which more closely mimic how cancer arises in humans.

Interphone compared surveyed cell phone use in 6,420 people with brain tumors to that of 7,658 healthy people in 13 developed countries — Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden and the U.K. — to try to determine whether people with brain tumors had used their cell phones more than healthy people, an association that might suggest that cell phones caused the tumors.

Only one of the 20 Spalax tested (an animal that was more than 10 years old) developed malignant tumors after exposure to one of the carcinogens.

They propose that normal tissue becomes primed for cancer when oncogenes are activated and tumor suppressor genes are silenced or lost, but that cancer develops only when a cell in the tissue reverts to a more primitive, embryonic state and starts dividing.

By tracking and understanding which host cell pathways are manipulated by these T. gondii proteins, scientists can identify potential new targets to develop more effective therapies against highly aggressive solid tumors.

More discouraging news about hormone replacement therapy for menopausal women appeared in June: Women taking Prempro, the most widely prescribed pill containing both estrogen and progestin, are more likely to develop Alzheimer's and to have early breast tumors that go undetected by mammogrMore discouraging news about hormone replacement therapy for menopausal women appeared in June: Women taking Prempro, the most widely prescribed pill containing both estrogen and progestin, are more likely to develop Alzheimer's and to have early breast tumors that go undetected by mammogrmore likely to develop Alzheimer's and to have early breast tumors that go undetected by mammograms.

By better understanding the tumor microenvironment we can develop strategies and treatment options to neutralize its oncogenic influence and more effectively attack the tumor itself.

The mice appear younger and more robust than comparably - aged normal mice, have better muscle tone, and do not develop age - related tumors.

«We found that many more mice developed tumors when given the cells that we had engineered to have these stem cell characteristics, and they had a much higher incidence of metastasis in the lungs,» Kilian said.

Rather than artificially triggering cancer by engineering genetic mutations, this model more closely mimics human liver cancer in that tumors develop as a natural consequence of non-alcoholic steatohepatitis (NASH), a chronic metabolic disorder that causes liver damage, fibrosis and numerous cell mutations.

That is why researchers more often rely on faster - developing indicators of (apparently) improved health: tumor shrinkage in cancer, lowered blood - sugar levels in diabetes, reduced brain plaque in Alzheimer's, lowered bad cholesterol or elevated good cholesterol in heart disease.

Little is known about how CNS - PNETs develop, although these tumors are more aggressive than other PNETs and have an overall survival rate of only about 20 percent.

AFP reports that Israeli researchers found that frequent cell phone users — described as people who chatter on mobiles more than 22 hours a month — had a nearly 50 percent higher risk than others of developing a tumor on the parotid gland (the largest of the salivary glands on the side of the face just in front of the ear).

They developed tumors more frequently and suffered from hormone imbalances, according to the study.

Of particular interest are how tumor - specific metabolic changes promote oncogenic progression and how these changes can be exploited to develop more effective treatment options.

Highlight what can be learned from the tumor microenvironment that might allow better, more effective therapeutics to be developed

«In a tumor, similarly, regions that develop these kinds of shapes may activate cells that can then escape and form more tumors.

Dozens of other studies have found that animals exposed to light at night develop tumors more readily than do those kept in the dark.

In the meantime, he adds, gaining a better understanding of aggressive NF1 - related tumors allows researchers to develop more realistic models of these cancers in the lab.

Now, MIT engineers have developed a far more sensitive way to reveal ovarian tumors: In tests in mice, they were able to detect tumors composed of nodules smaller than 2 millimeters in diameter.

If we validate this study in similar, but larger groups of patients, we can develop a test based for CFS breaks; the results would allow us to place patients in one of two categories: those whose tumors do not have CFS breaks and who would likely do well with local treatment alone (e.g. radiotherapy or surgery); and, those patients whose tumors do have CFS breaks and would need a more complex treatment protocol, in addition to RT or surgery, to combat distant spread.»

However, if these mice developed tumors, these were pervaded by significantly more blood vessels and, in addition, grew faster than in fellow animals with functioning Tie2 receptor.

Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread.

Mice that were given antioxidants developed additional and more aggressive tumors.

His laboratory at the German Cancer Research Center in Heidelberg and at the Medical Faculty Mannheim of Heidelberg University is studying the mechanisms of metastasis with the goal to develop more gentle supportive adjuvant therapies for tumor patients without detectable metastases following surgery of the primary tumor.

When using a well established model of colorectal cancer, the researchers observed that dietary emulsifier consumption was sufficient to make the animals more susceptible to developing colonic tumors because this created and maintained a pro-inflammatory environment associated with an altered proliferation / apoptosis (cell death) balance.

In their search for novel, tumor - specific therapies that could target multiple brain metastases without damaging adjacent tissues, the research team first developed a mouse model that more closely mimics what is seen in patients.

Nguyen is developing ways to guide surgeons during tumor removal surgery by using fluorescent compounds to make tumor cells — and just tumor cells — glow during surgery, which helps surgeons perform successful operations and get more of the cancer out of the body.

During this period, the mice on the high - fat diet gained 30 to 50 percent more body mass than mice fed a normal diet, and they developed more intestinal tumors than mice on a normal diet.

«More studies are warranted to confirm the deleterious effect of antibiotic use in large prospective trials and to develop novel diagnostic tools based on gut microbiota in cancer patients, to predict response / resistance to ICIs and identify the key microbiota signatures for each tumor site,» the researchers wrote.

The data on self - reported problems is more mixed, and there is some evidence to suggest that brain tumor survivors may have inaccurate perceptions of their own social functioning compared with typically developing peers (Salley et al., 2014),» added Dr. Devine.

«If we didn't know the spectrum of the mutations that were in our patients» tumors, we couldn't begin to develop more appropriate therapies because we were sort of playing in the dark.»

In both cases, paclitaxel changed the tumor microenvironments in three ways, all more conducive to metastasis: The microenvironment had more of the immune cells that carry cancer cells into blood vessels, it developed blood vessels that were more permeable to cancer cells, and the tumor cells became more mobile, practically bounding into those molecular Lyfts.

Researchers can't explain why male rats get heart tumors but some believe male rats developed these tumors because they were much bigger in size and likely exposed to more radiation than their female counterparts.

A sensor developed at A * STAR can detect bladder cancer cells and track tumor progression Microelectronic engineers in Singapore have developed and tested sensor technology that can detect an... Read more

Blastoma: Tumors formed from embryonic tissue or developing cells are known as blastomas and are more common in children than adults.

His lab has extensive experience evaluating and modulating T cell responses to tumors and viruses, including introducing genes into T cells to impart specificity and modulate function, designing strategies to overcome tolerance and enhance in vivo activity, and developing mouse models that more accurately model human immune responses to candidate vaccines.

In addition, our investigators have used epigenetic biomarkers to: develop screening tests for cancer; help guide surgeons in removing cancerous tumors; predict drug resistance; and, pinpoint more aggressive cancers.

5/21/2007 Decoding Gene Expression in Cancer Tumors Using Non-Invasive Imaging By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego (UCSD) School of Medicine has developed tools that may some day allow physicians to view a... More...

The challenge takes on even more urgency with recent developments, including a federal administration now more open to exploring the potential of stem cells, the recent FDA approval of a human trial involving embryonic stem cells, as well as the reported case of a young boy who developed a brain tumor four years after receiving a stem - cell treatment for a rare genetic disorder.

I am developing mathematical and statistical tools to disentangle tumor cell population structure, enabling an earlier and more accurate diagnosis of the disease and better - informed clinical decisions.

The removed gene region thus appears to act as an important gene switch promoting cancer, and without it tumors develop much more rarely.

Often, metastasized tumor cells spread more rapidly than primary tumor cells and it is not uncommon to develop multiple tumors in several areas of the brain.