«There's an ongoing need to
develop new gene synthesis techniques,» said Calin Plesa, a UCLA postdoctoral research fellow and co-first author of the paper.
The new Salk tool, called CasRx, opens up the vast potential of RNA and proteins to genetic engineering, giving researchers a powerful way to
develop new gene therapies as well as investigate fundamental biological functions.
A Glaxo vet heads over to Genenta to help
develop new gene therapy.
Dartmouth Institute for Quantitative Biomedical Sciences (iQBS) researchers
developed a new gene expression analysis approach for identifying cancer genes.
The researchers propose that the rapid evolution and wholesale remodeling of the Y chromosome in both species have been caused by several mechanisms, including the competitive advantage gained by
developing new genes for sperm production.
Researchers at the University of Florida have
developed a new gene therapy that might help combat multiple sclerosis
Researchers at the University of Florida have
developed a new gene therapy that shows promise in fighting multiple sclerosis (MS).
Researchers at the University of Florida have
developed a new gene therapy that might help combat multiple sclerosis (Credit: < a href ="https://depositphotos.com/45812893/stock-photo-man-using-his-wheelchair.html" rel="nofollow"> minervastock / Depositphotos )
Researchers at the University of Florida have
developed a new gene therapy that might help combat multiple sclerosis (Credit: minervastock / Depositphotos)
Researchers have
developed a new gene editing tool that is more efficient and easier to use.
Not exact matches
• Myonexus Therapeutics, a
New Albany, Oh. - based clinical - stage biotechnology company
developing transformative
gene therapies for limb - girdle muscular dystrophies, raised $ 2.5 million in seed funding.
Gene Zimon §
Gene Zimon is the Founder and President of EDGE Advisors which assists early stage companies
develop their product and go - to - market strategies, and advises institutional investors and other companies on investments in and acquisitions of
new technologies.
By invalidating key parts of Myriad's patents, the court has removed a bar that prevented labs using
new technology from
developing and selling broader one - time tests that search for all known cancer risks, including the BRCA
genes, geneticists said.
«Testing of
new rice varieties that have the SPIKE
gene is under way in multilocation trials across several
developing countries in Asia, including Indonesia.
We believe that these will contribute to food security in these areas once the
new varieties are released,» said Dr. Tsutomu Ishimaru (in photo above), an IRRI and JIRCAS rice breeder who is now leading the work to
develop new varieties with the SPIKE
gene.
«Using a
new approach of combining molecular identification of the SPIKE
gene and conventional breeding, we have
developed rice, with the SPIKE
gene, that has higher yield when compared with an equivalent rice without the
gene,» Dr. Kobayashi said.
«Rice genetics is all about understanding the
genes of rice so that we can
develop new and improved rice varieties to help farmers produce more rice, with fewer resources and despite challenges like climate change,» said event convener, Dr. Eero Nissila, head of the Plant Breeding, Genetics, and Biotechnology Division at IRRI.
The EC has historically supported IRRI's work to conserve the genetic diversity of rice, understand the function of rice
genes, and
develop new rice varieties, particularly for use in difficult growing environments.
We've been hearing about better male birth control for years now, but in recent weeks two
new promising options have come to light: RISUG (reversible inhibition of sperm under guidance), being
developed by an Indian scientist, Sujoy Guh, and the discovery of a
gene, Katnal1, critical for sperm production; if scientists can tweak the
gene with a pill, sperm production will be stalled.
And researchers generally shied away from clinical research on any patented
genes — a 2003 survey found that 53 percent of genetics labs decided not to
develop a
new genetic test because of a patent or license.
Michael Kaplitt, a neurosurgeon at Weill Cornell Medical College in
New York, whose lab develops gene therapies for brain disorders, teamed up with Greengard and other colleagues in the new stu
New York, whose lab
develops gene therapies for brain disorders, teamed up with Greengard and other colleagues in the
new stu
new study.
An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has
developed a
new technique for identifying
gene enhancers — sequences of DNA that act to amplify the expression of a specific
gene — in the genomes of humans and other mammals.
A genetics research team at Johns Hopkins Medicine has solved a dilemma facing researchers who use genomewide association studies (GWAS) by
developing a
new approach that strategically «filters» which
genes are worth further study.
As well as understanding the implications of finding this
new variant of the botulism
gene cluster in a non-clostridial species of gut bacterium, the team are interested in exploring how it might help in
developing new treatments for diseases.
In 2006, Paul Greengard, a neuroscientist at the Rockefeller University in
New York, and his colleagues created mutant mice lacking the
gene, and found that the animals
developed depression - like behaviours.
As in a game of telephone, each time a
gene gets passed from one microbe to another, slight differences
develop that reflect the DNA dialect of its
new host.
Using a modified version of the CRISPR genome - editing system, MIT researchers have
developed a
new way to screen for
genes that protect against specific diseases.
«Neuroscientists are using these
new gene - editing and molecular tools to
develop potential therapeutic targets across multiple disease fronts.»
«Fibroblast growth factor receptor inhibitors are
new therapies being
developed in clinical trials for patients whose cancer cells have genetic alterations in this family of
genes,» says Roychowdhury, a member of the OSUCCC — James Translational Therapeutics Program.
Moreno's first job in the lab — helping a postdoc
develop a mutagenesis technique to identify
new genes involved in organ development and positioning — earned him a second - author paper in Science just a couple of years into his Ph.D..
To discover this, Hui Liu,
Gene Robinson, and Eric Jakobsson of the University of Illinois developed new computational tools to analyze patterns of gene conservation across a wide range of animals, for genes activated and inhibited in the honey bee brain by exposure to a chemical communication signal that triggers al
Gene Robinson, and Eric Jakobsson of the University of Illinois
developed new computational tools to analyze patterns of
gene conservation across a wide range of animals, for genes activated and inhibited in the honey bee brain by exposure to a chemical communication signal that triggers al
gene conservation across a wide range of animals, for
genes activated and inhibited in the honey bee brain by exposure to a chemical communication signal that triggers alarm.
A team of 18 University of California San Diego School of Medicine and Moores Cancer Center researchers has
developed a
new tool to analyze an often overlooked aspect of cancer genetics — an alteration that results in the loss or gain in a copy of a
gene.
A team of researchers at the University of Central Florida is using breakthrough
gene - editing technology to
develop a
new screening tool for Parkinson's disease, a debilitating degenerative disorder of the nervous system.
James Adjaye, a biologist at the Max Planck Institute for Molecular Genetics in Berlin, Germany, says that further work needs to be done before scientists can be sure that the
genes found in the
new work are actually indicate that an embryo will
develop into a baby.
«If this approach works in humans, it will really change the conversation that providers have with patients,» Scadden said, especially for those «who have these underlying genetic disorders and for who the
new gene - editing and
gene therapy techniques are being
developed.»
«Genetics researchers close in on schizophrenia: 50
new gene regions that increase risk of
developing schizophrenia.»
Although the researchers suspected that having more copies of the
gene sequence might confer a greater degree of resistance, they had no way of testing their suspicions before the
new assay was
developed.
The findings point to a possible
new risk factor for
developing celiac disease in people with celiac disease risk
genes.
The number of copies of the resistance
gene varies among cultivars; a
new method,
developed by University of Illinois researchers, is able to efficiently quantify this variation for the first time.
The
developing brain undergoes rapid and tightly coordinated changes in a molecular process known to help regulate
gene activity, a
new study shows.
Gene variants common in people of Asian and European ancestry, for instance, make them more prone than those of African origin to
developing severe dengue shock syndrome, according to a
new study in PLOS Neglected Tropical Diseases.
For example, genetically engineered organisms used in the research laboratory to
develop new chemical synthesis methods are not likely to require the same level of public dialogue as products that have more uncertainty associated with them, such as organisms with
gene drives, which enhance organisms» ability to pass certain genetic traits on to their offspring.
For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of
new technologies to provide insights into human brain circuitry and function through the Brain Research through Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the
gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to
develop and test a «curative therapy» for the first molecular disease: sickle cell disease.
«This is a seminal step in identifying key pathways and molecules involved in kidney cancer so that specific therapies that target these
new genes can be
developed to treat this cancer.»
In addition, using methods for the analysis of regulatory networks
developed by the Califano lab in the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (
gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce
new hair growth.
Lisa Harris, of Dalton High School in
New York City, won this year's top Siemens prize for individuals — a $ 100,000 college scholarship — for developing a new method to detect carriers of a gene responsible for cystic fibros
New York City, won this year's top Siemens prize for individuals — a $ 100,000 college scholarship — for
developing a
new method to detect carriers of a gene responsible for cystic fibros
new method to detect carriers of a
gene responsible for cystic fibrosis.
The study was inspired in part by the complex effects of a
new melanoma drug
developed by the biotech companies Plexxikon and Roche that blocks a protein made by a mutated
gene called BRAF.
Women with a family history of two or more immediate family members (mother, sister, daughter) with breast or ovarian cancer or with a positive genetic test for mutations in the BRCA1 or BRCA2
genes may be advised to consider having both breasts removed, because they are at high risk of a
new cancer
developing in the other breast.
For one such project, the team
developed a
new software tool called GppFst that allows researchers to differentiate genetic drift — a neutral process whereby
genes and
gene sequences naturally change due to random mating within a population — from genetic variations that are indicative of evolutionary changes caused by natural selection.
First author Professor Martin Hrabe de Angelis, Director of Institute of Experimental Genetics at the Helmholtz Zentrum München, who invented the mouse clinic concept, said: «Our findings with regard to the
genes examined are now available to the scientific community as a valid data set, which can be downloaded free of charge from the IMPC (International Mouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can
develop and test
new hypotheses.»