However, these tumors may display intrinsic or acquired resistance to treatment, and classifiers of HER2 - positive tumors are required to improve the prediction of prognosis and to
develop novel therapeutic interventions.
Oberman's research interest lies in using electrophysiological techniques (such as EEG and TMS and TCS) to investigate neural circuits whose dysfunction may account for the behavioral pathology seen in autism spectrum disorders with the long term goal of
developing novel therapeutic interventions.
Not exact matches
Koo and colleagues are now working on
novel therapeutic approaches for targeted
interventions, which can be potentially
developed for clinical use.
His research aims to determine the underlying biochemistry and molecular mechanisms of these diseases, then
develop and test
novel therapeutic interventions through rigorous translational and clinical trial research.
The lab recently
developed novel LumiFluor ® optical reporters and are now implementing these reporters for the non-invasive, high resolution in vivo optical imaging of tumor development, progression, and response to
therapeutic intervention in genetically engineered mouse models (GEMM) of cancer.
A deeper understanding of these axes provides a new framework for
developing novel therapeutic targets and optimising personalised
interventions.
Dr. Jung is board certified in veterinary cardiology and in addition to his teaching and clinical responsibilities, investigates mechanisms of heart failure and is
developing novel diagnostic and
therapeutic interventions.