Although cancer immunotherapy is changing the paradigm of how cancer is treated, there is an urgent need to
develop predictive biomarkers to identify patients who are most likely to benefit from various immunotherapeutic strategies.
Not exact matches
Such knowledge would help
develop better
predictive biomarkers and more efficient targeted therapy to improve the clinical outcome.»
«We now have
developed a better panel of
biomarkers that are
predictive across several psychiatric diagnoses.
«The LSC17 score is the most powerful
predictive and prognostic
biomarker currently available for AML, and is the first stem cell - based
biomarker developed in this way for any human cancer,» says Dr. Wang.
GeneAssess, Inc., is dedicated to
developing its breakthrough discovery of the FRY gene as a
predictive biomarker for breast and other cancers.
[30, 31] In
developing candidate
predictive biomarkers, several issues will make validation and adoption challenging in RCC since we may not know which tissue type (primary or metastatic tissue) to test and how many biopsy cores are needed.
Christina's research leverages genome - scale data, coupled with computational modeling and iterative experimentation in order to define the molecular determinants and dynamics of tumor progression and to
develop predictive and prognostic
biomarkers.
Our approach to achieving this goal focuses on three objectives: (1) to
develop a reliable,
predictive panel of
biomarkers (including both biological and bio-behavioral measures) that can identify children, youth, and parents showing evidence of toxic stress, and that can be collected in pediatric primary care settings; (2) to conduct basic, animal and human research on critical periods in development and individual differences in stress susceptibility, thereby informing the timing and design of a suite of new interventions that address the roots of stress - related diseases early in the life cycle; and (3) to build a strong, community - based infrastructure through which scientists, practitioners, parents, and community leaders can apply new scientific insights and innovative measures to the development of more effective interventions in the first three postnatal years.
His research focuses on
developing new therapies and identifying novel prognostic and
predictive biomarkers for canine lymphomas.