Affected cats
developed amyloid deposits primarily in their kidneys resulting in chronic kidney disease typically before they were 6 years of age.
Not exact matches
The findings, published in the journal Nature Neuroscience, could help explain how some older adults with beta -
amyloid deposits in their brain retain normal cognitive function while others
develop dementia.
A team of scientists at Sweden's Linköping University have
developed a molecular probe that can detect an array of different
amyloid deposits in several human tissues.
Male homozygous mice for hIAPP
develop T2D - like clinical and pathologic alterations, including hyperglycemia, reduced insulin secretion, IAPP
amyloid deposits, and β cell loss (Janson et al., 1996).
In homozygosis, male Tg mice spontaneously
develop IAPP
amyloid deposits, which are associated with selective β cell death, impaired insulin secretion and hyperglycemia (Janson et al., 1996).