Not exact matches
Thanks to powerful gene - sequencing techniques
developed in the past two decades during the race to decode the
human genome, researchers are beginning to reconstruct what our ancestors»
microbiomes looked like, potentially going back thousands of years.
Mice raised with
human microbiomes never
develop mature immune systems, which may explain the rise in immunological illnesses
Researchers speculate that when microbes mix,
humans may take bacterial souvenirs from one another, a potential contributor to how we
develop our individual
microbiomes.
Although common in
humans, domestic pets, and zoo animals, periodontal disease does not typically
develop in wild animals, leading to speculation that it is an oral
microbiome disease resulting from modern
human lifestyles.
A team of investigators from Brigham and Women's Hospital and the University of Massachusetts have
developed a suite of computer algorithms that can accurately predict the behavior of the
microbiome — the vast collection of microbes living on and inside the
human body.
The intestinal microbiota of healthy
humans progressively
develops in complexity from birth until adulthood, where a stable
microbiome is established for the majority of an individual's adult life (Arumugam et al., 2011; Jalanka - Tuovinen et al., 2011; Durbán et al., 2012).
When they are given a
microbiome in the form of a fecal transplant from a
human donor, however, they plump up within a day or two because the bacteria help them digest their food and
develop a proper metabolism.
Developing a Bacteroides System for Function - Based Screening of DNA from the
Human Gut
Microbiome — Kathy N. Lam — mSystems
He has
developed an algorithm that identifies the biosynthetic genes in bacterial genomes and has applied this algorithm to the
human microbiome.
Maybe one day when we know more about the
microbiome in the
human gut, scientists could
develop a computer program to predict how the different types of food we eat, or antibiotics we take, affect the gut
microbiome.
A Unified
Microbiome Initiative would
develop the transformative tools and research teams we need to harness the power of these communities to improve
human health, agricultural productivity, bioenergy production, and environmental stability,» Chun said.
With support from numerous federal agencies, the initiative promises to
develop scientific tools and training programs centered around the
microbiome to combat chronic
human diseases, climate change, food security, and more.
In the proposed partnership between Addis Ababa University (AAU) and J. Craig Venter Institute (JCVI), the objective is to build genomics capacity at AAU and to apply newly
developed skills towards understanding the relationships of active TB disease with Mtb strain type diversity and host components such as the
human respiratory
microbiome and protein - based analysis of immune responses in the respiratory tract.
Her laboratory focuses on (1) the use of next generation sequencing to define the
microbiome and host immunologic features in patients with
human diseases and (2)
developing custom computational tools for the identification of novel
human commensals and pathogens in these inpatient populations, and (3) using statistical and functional biological methods to understand the complex interplay between the
human microbiome and host biology.
Most diseases don't
develop because the
human genome is inherently flawed, but rather because of unfavorable interactions that take place between the
human genome and its environment, including the
human microbiome.
Known collectively as the
microbiome, these trillions of live bacteria found in the
human body influence everything from your immune system to your likelihood of
developing chronic degenerative disease.
By using data to better understand the
human microbiome, more effective diagnostic tools and therapies can be
developed.