Sentences with phrase «developing aggressive disease»
This choice is challenging, because medical science can not reliably identify those men who are at risk for developing aggressive disease and may benefit from active treatment.
https://www.sciencedaily.com/ Not exact matches
New Yorkers need to be protected from the disease through aggressive preventive action, and this groundbreaking legislation, developed in partnership with the City Council, is exactly that.»
DNMT3A is among the most frequently mutated genes in an aggressive type of leukemia, and it plays a significant role in how this disease develops.
By age 80, more than 50 percent of men will develop prostate cancer but not all will have the aggressive, deadly form of the disease.
«We thought that if we could understand how some people live several years with this most aggressive disease, we might be able to develop a new therapeutic strategy.»
Scientists at Cedars - Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk.
«New tumor analysis method identifies high - risk prostate cancer: Cancer cells» genetic pathways show which patients are likely to develop aggressive types of the disease.»
Researchers developed a new clinical approach to increase the efficiency of treatment that increased the median survival to 22 months — bringing much needed hope to those affected by this aggressive disease.
Based on recent information on the mechanisms of chemotherapy, a team of researchers of the McGill University Health Centre (MUHC) developed a new clinical approach to increase the efficiency of treatment in glioblastomas that increased the median survival to 22 months — bringing much needed hope to those affected by this aggressive disease.
Given the role of Msi in promoting aggressive disease, the investigators partnered with Robert MacLeod PhD, vice-president of oncology drug discovery at Ionis Pharmaceuticals, to develop next - generation antisense oligonucleotide (ASO) inhibitors against Msi.
After following 154 men with low - risk prostate cancer for 38 months, the investigators found that low levels of free testosterone were significantly linked with an increased risk of developing more aggressive disease.
Frequent exposure to ultraviolet (UV) rays for individuals under the age of 35 increases the risk of developing melanoma — the most aggressive and deadliest form of skin cancer — by 75 percent, according to the Centers for Disease Control and Prevention.
Unfortunately, doctors currently have no reliable way of predicting which men will develop evidence of worsening or more aggressive disease during active surveillance.
The research ideas you develop at the workshop should: • Lead to the significant advancement of our understanding of sensor technologies suitable for liquid biopsy • Consider the practical challenges of low volume liquid usually taken for analysis and the inconsistency of sample preparation across point of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease
Men with BRCA1 / 2 mutations who develop prostate cancer tend to develop these cancers at an earlier age than average and may develop more aggressive forms of the disease.
They found that when an MS - like disease was induced in mice genetically engineered to be deficient in Tob1, the mice had significantly earlier onset compared with wild - type mice, and developed a more aggressive form of the disease.
Carriers of germline mutations in BRCA2 have at least five times greater risk of prostate cancer and frequently develop a more aggressive form of the disease.
Low Cholesterol May Shrink Risk for High - Grade Prostate Cancer Men with lower cholesterol are less likely than those with higher levels to develop high - grade prostate cancer, an aggressive form of the disease with a poorer prognosis, according to results of a Johns Hopkins collaborative study.
While men with the more aggressive form of the cancer make up about 5 % of the 180,000 to 200,000 cases of prostate cancer in the U.S. each year, and only 12 % will have these mutations, that population is still at considerably higher risk of developing advanced disease.
«Studies show that people who are low in vitamin D are at greater risk of developing MS, as well as having more frequent relapses and a more aggressive progression of the disease,» Kalb says.
The findings also hint that in coming years, it may be possible to use the panel not just among men with advanced disease but to distinguish between men who develop the slower growing type of prostate cancer from the more aggressive type.
One reason may be that men in the study seemed to develop Alzheimer's at a younger age than women and had a more aggressive form of the disease.
Influenced further by epigenomes, these changes are linked with impairment in the child's ability to respond to future biological and environmental stress, and increase the risk for physical and mental health disease later in life.49 - 52 This emerging research underscores the need to develop and test prevention and early, aggressive intervention strategies for children who have been victims of serious physical abuse.