The Purdue studies also found that vaccinated dogs were
developing autoantibodies to their own collagen.
The researchers, therefore, wanted to study whether the vaccine also increased the risk of
developing autoantibodies against beta cells in the pancreas and the occurrence of type 1 diabetes.
The results of the study showed no relation between vaccination and an increased risk of
developing autoantibodies or type 1 diabetes.
However, a new study of children from Sweden and Finland shows that the vaccine increased neither the risk of
developing autoantibodies against insulin - producing beta cells nor the occurrence of type 1 diabetes.
In a recent publication, CDI's technology was also used to
develop an autoantibody profile for neuropsychiatric lupus (2), a valuable diagnostic tool for a disease that typically lacks clear clinical signs.
The authors concluded that the vaccinated but not the unvaccinated puppies
developed autoantibodies to their own collagen.
We know that vaccinated dogs
develop autoantibodies to their own tissues and biochemicals, and we also know that these antibodies are markers for serious disease conditions — but we don't test for these autoantibodies when our dogs develop cancer.
On top of that, the Purdue study showed that vaccinated dogs
develop autoantibodies to their own DNA; perhaps vaccinated breeding dogs are passing along damaged DNA and that is a part of the picture.
Perhaps most worryingly, the Purdue studies found that the vaccinated dogs had
developed autoantibodies to their own DNA.
The vaccinated Purdue dogs also
developed autoantibodies to laminin, which is involved in many cellular activities including the adhesion, spreading, differentiation, proliferation and movement of cells.
The vaccinated, but not the non-vaccinated, dogs in the Purdue studies
developed autoantibodies to many of their own biochemicals, including fibronectin, laminin, DNA, albumin, cytochrome C, cardiolipin and collagen.
If dogs
develop autoantibodies to albumin as a direct result of routine vaccination, their neurological function is but one likely casualty.
Recent work at Colorado State University showed that most kittens
developed autoantibodies to their own kidney tissues after being vaccinated for distemper.
Some years ago, I researched the implications of what might happen to vaccinated dogs in a Purdue University study who
developed autoantibodies to their own biochemicals.
Not exact matches
Type 1 diabetes is an autoimmune disease that can be detected in asymptomatic individuals by the presence of islet
autoantibodies that
develop in children.
When a strain of mice genetically destined to
develop a form of TLR7 - dependent lupus was crossbred with a strain in which TREML4 expression was suppressed, offspring lacking TREML4 were protected from the development of lupus - associated kidney failure and had significantly lower blood levels of inflammatory factors and
autoantibodies than did mice expressing TREML4.
As they studied these children more intensively, they learned that those with two or more different kinds of these
autoantibodies will eventually
develop diabetes, though sometimes not for many years.
The team
developed a «chimeric
autoantibody receptor,» or CAAR, that displays fragments of the autoantigen Dsg3 — the same fragments to which PV - causing antibodies and their B cells typically bind, as Payne's laboratory and others have shown in prior studies.
Since GAD
autoantibodies are closely associated with
developing type 1 diabetes, the authors note that it is surprising that only 10 to 20 per cent of people with APECED
develop diabetes.
To investigate why the APECED patients were not
developing diabetes, they compared blood samples from eight APECED patients with type 1 diabetes with 13 APECED patients who had GAD
autoantibodies but had not
developed diabetes.
Dr. Li's project will
develop a new technology to identify all
autoantibodies in the blood and simultaneously quantify their activities like a fingerprint map with thousands of
autoantibody peaks at different activities.
They determined which of these SNPs are different in TEDDY participants who had
developed type 1 diabetes versus those who had Islet cell
autoantibodies versus those who still had neither.
Using a panel of newly
developed blood tests, they were able to detect cardiac
autoantibodies in 15 of 18 (83 %) patients.
Currently, the best approach for predicting those at risk for
developing T1DM before symptoms appear is by measuring
autoantibodies to islet cell antigens in the pancreas.
These mice
develop spontaneous autoimmune - like signs, including splenomegaly, accumulation of activated T cells and
autoantibodies, and pathological features of inflammation in the intestine.
High microsomal and thyroglobulin
autoantibody titres were present in six of 31 patients (19 %) receiving iodine, and iodine - induced hypo - and hyperthyroidism
developed in four and two of them, respectively.