Sentences with phrase «developing drug»

Unfortunately, he adds, developing a drug that stops MSH2 isn't an option, because people could become even less healthy if they lose some of their DNA repair capability.

NeuroPhage is initially developing drug candidates to treat Alzheimer's and Parkinson's diseases, in which multiple misfolded proteins can exacerbate disease progression, and the Company is also targeting several rare systemic amyloidosis diseases.

NeuroPhage is initially developing drug candidates to treat Alzheimer's and Parkinson's diseases and several rare systemic amyloidosis diseases.

Sofia will receive the 2016 Lasker - DeBakey Award on Sept. 23 along with Charles Rice, Ph.D., of Rockefeller University and Ralf Bartenschlager, Ph.D., of Heidelberg University, who were recognized for their work in developing systems essential to hepatitis C research, which Sofia used in developing the drug, sofosbuvir.

And this could scare people off from funding a study or developing a drug in the first place.

«We are committed to quickly developing this drug and are finalizing what we believe will be a rapid development path for this drug in all types of SMA.

Professor Sahakian says: «We need a way of treating the cognitive symptoms of schizophrenia, such as problems with episodic memory, but slow progress is being made towards developing a drug treatment.

Developing a drug that targets Nef, however, will first require that researchers discover a molecule to interrupt that assembly.

Imagine developing a drug designed to inhibit a protein that helps cancer cells proliferate and survive only to find that the drug does not perform very well in the clinic.

This similarity suggests that researchers should target the underlying process in the different varieties of the disease, he says, for example by developing a drug to prevent dystrophin from breaking down.

A team from Sydney's Westmead Institute for Medical Research is a step closer to developing a drug to treat life - threatening fungal infections that cause more than 1.6 million deaths annually.

The finding raises the possibility of developing a drug that would prevent HIV - 1 from binding to bicaudal D2, thus stranding the virus in the cytoplasm.

The broad idea is to de-link the payment a company receives for developing a drug from its subsequent sales.

Marrazzo admits, however, there are many questions about how his firm should be rewarded for the $ 400 million it has spent developing the drug, given that healthcare systems are geared to paying for drugs monthly rather than facing a huge upfront bill.

A fund backing that group of research projects might expand the chances of developing a drug that could, at a minimum, slow the progression of the disease.

Further ahead, he envisions developing a drug that could block the channel, thereby triggering instant sobriety or preventing a person from getting drunk.

The reason I chose this as a topic was because I write this monthly feature that tracks how a technology starts its life from basic science, how it's transferred from basic science findings into the early phases of the technology, and this is a classic example because it goes from an understanding about how evolution works all the way to the early phases of developing a drug.

Our next step is to investigate the effects of targeting the Erk - Ras - ETS pathway in more complex animals, such as mice, with a view to developing a drug regime that could be suitable for testing in humans.

«No one's entertained the idea of developing a drug that affects FIH before, but I think our study will lead to greater examination of that possibility,» says Professor Johnson.

This is an important step in developing drug treatments that target certain genes or certain products derived from the intestinal bacteria.

The response we've seen in flies to low doses of lithium is very encouraging and our next step is to look at targeting GSK - 3 in more complex animals with the aim of eventually developing a drug regime to test in humans.

She had recently rationalized her work to a relative, explaining that, yes, she was developing a drug, but it's still in the early stages — so if a hundred individual things go right, then maybe her drug would become real and useful in about 15 years.

Scientists at Glyscend are developing a drug that could mimic the effect — but with no surgery required.

And they could make it possible to predict a person's individual risk for developing a drug addiction.

Developing the drug cheaply and plentifully was essential for national security.

Infant antacid exposure was linked to a doubling of the risk for developing food allergies, and a 50 percent increase in the risk for developing drug allergies and a hypersensitive immune reaction to foreign toxins, such as a bee sting (anaphylaxis).

If you know exactly how to be a good parent, you can protect your children from developing drug and alcohol abuse, anti-social behavior, eating disorders, depression, and anxiety.

Like, what, everyone's fired when they finish developing the drug?

Biotechs can win either by addressing a very large market or developing a drug with a lot of pricing power.

Portola is also developing a drug to rival Xarelto and Eliquis.

Lilly had spent 15 years developing the drug and many experts believed it would be first to the gate in securing an FDA approval for slowing Alzheimer's progression.

Developing a drug pipeline posed new challenges for the small company, of course.

Biotech and pharma companies will get a smaller tax credit for developing drugs for rare diseases.

«And as long as that happens, your insurance company is not going to pay your bill if you take a drug and the pharmaceuticals are not going to develop the drugs because if nobody is going to pay for their use, why spend the money on that?»

I've been interested in what 23andMe is doing ever since I heard they were planning to develop drugs based on genetic information.

Half a million people develop drug - resistant TB each year; a UK parliamentary group in 2015 projected it will kill 75 million and cost the world $ 16.7 trillion over the next 35 years.

Within weeks of her diagnosis in 1996, Giusti began disrupting the myeloma research culture — getting isolated doctors and scientists to share data, and building an unheard - of consortium to develop drugs.

Companies like U.S. biotech giant Gilead and the U.K.'s GlaxoSmithKline (the majority stakeholder in global HIV partnership ViiV Healthcare) have developed drugs that drastically lower the chance of HIV infection — or which simply lower the number of drugs you have to take to treat it, consequently curbing the risk of toxic side effects while simplifying medical regimens.

UniQure, for example, has developed a drug called Glybera, which is essentially a virus that reverses the effects of LPLD, a disease that prevents people from breaking down fats and can cause increased risk of pancreatitis.

BOSTON, April 20 (Reuters)- Alnylam Pharmaceuticals Inc said on Friday that Dicerna Pharmaceuticals Inc will pay it $ 25 million in cash and stock to resolve a lawsuit claiming it stole trade secrets about gene - silencing technology used to develop drug treatments.

These favorable regulatory policies are helping Chinese companies grow faster and develop drugs and medical devices cheaper than the U.S, explained Qiming Venture Partners managing partner Nisa Leung.

As I've previously reported, Roivant and its federation of biopharma companies focused on developing drugs in specific disease spaces is attempting a very new form of pharmaceutical R&D.

To this end, Calico has also forged a partnership with a Chicago - based biopharmaceutical company called AbbVie, in order to develop drugs that will tackle aging and age - related diseases such as neurodegeneration and cancer.

While it might cost $ 3 to $ 4 billion to develop a drug in the U.S., the same development could be done in China for about $ 30 to $ 40 million, Leung explained.

What Boger wants is to create a better way to develop drugs: through a process called structure - based design in which scientists build up a new drug, atom by atom, after determining the type of molecule that might interrupt the disease process.

I applaud the estimated 800 clinicians, scientists and companies working on ALS — quietly, bravely laboring away, treating patients and testing and developing drugs to halt ALS's suspected genetic origins.

Genentech is one of the companies developing drugs that go after the amyloid hypothesis.

Roughly a decade ago Pfizer (PFE) developed a drug based on an antibody that it, too, licensed from Medarex — but gave up on it, says Allison, when the drug didn't immediately shrink tumors.

While Ebola spread, companies ranging from the $ 40 billion British pharma giant GSK to nine - employee startup Mapp Biopharmaceutical all worked quickly to develop drugs to combat it, though no one is yet to create a proven antidote.

Alnylam has been developing drugs that target gene expression in order to prevent to production of certain biological material which can cause devastating diseases.