Sentences with phrase «developing epidermis»
A fully developed epidermis model is used to study phototoxic effects.
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An international team led by King's College London and the San Francisco Veteran Affairs Medical Center (SFVAMC) has developed the first lab - grown epidermis — the outermost skin layer — with a functional permeability barrier akin to real skin.
The new epidermis, grown from human pluripotent stem cells, offers a cost - effective alternative lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common skin disorders.
Mammalian hairs and avian feathers develop from a similar primordial structure called a «placode»: a local thickening of the epidermis with columnar cells that reduce their rate of proliferation and express very specific genes.
We focus on squamous tissues, the skin epidermis and the lining of the oesophagus, using transgenic models, novel sequencing approaches, live imaging and single cell analysis to uncover key steps in cancer development, with aim of developing rational interventions to decrease cancer risk.