Sentences with phrase «developing human brain»

«Atlas of developing human brain launched by researchers: Gene expression study may provide insights into autism, other neurodevelopmental disorders.»

Researchers, however, say they are still a long way from determining exactly what effects cannabinoids have on developing human brains.

Rather, as Wendy explained, «we're able to see, given the fully developed human brain, what happens when it has to make a language out of nothing.»

In the study, Rana's team first made sure their organoid model was truly representative of the early developing human brain.

Seeing a developing human brain and studying the (funny) ways it interacts with the outside world was much more fun than figuring out synaptic plasticity during mouse development.

Studies looking at the posterior fossa of the developing human brain showed low H3K27me3.

A new atlas of the developing human brain should offer clues.

The result is called the BrainSpan Atlas of the Developing Human Brain (Nature, DOI: 10.1038 / nature13185).

This should help narrow down when and where such conditions begin in the developing human brain.

In a paper publishing August 7th in the Open Access journal PLOS Biology, researchers at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI - CBG) succeeded in mimicking the sustained expression of the transcription factor Pax6 as seen in the developing human brain, in mouse cortical progenitor cells.

Of course, as Kosofsky said, we just don't know what caffeine during pregnancy does to a developing human brain.

«We couldn't have done this even two years ago,» State said, «because we didn't have the key ingredients: a set of unbiased autism genes that we have confidence in, and a map of the landscape of the developing human brain.

There is a clear connection between Clara Moskowitz's article about an investigation of whether space and time could be made of tiny informational building blocks [«Tangled Up in Spacetime»] and Juergen A. Knoblich's article on growing part of the developing human brain in the lab for research [«Lab - Built Brains»].

Garcez and her colleagues at the Instituto D'Or in Rio de Janeiro in Brazil are starting experiments in which they will infect so - called cerebral organoids — tiny models of the developing human brain — with Zika virus and see whether their development is affected.

«This is an attempt to generate an unbiased view of what genes are expressed in every cell type in the developing human brain in order to highlight potential cellular vulnerabilities in patient - relevant mutations,» said Nowakowski.

From these «jack - of - all - trades» cells, they generated brain organoids — small three - dimensional tissues which resemble the structure and organization of the developing human brain.

«This study focused on the development of the neocortex, but we aim to analyze multiple brain regions and developmental stages to achieve a more comprehensive atlas of cell types in the developing human brain,» Kriegstein said.

Now researchers at UC San Francisco have taken the first step towards a comprehensive atlas of gene expression in cells across the developing human brain, making available new insights into how specific cells and gene networks contribute to building this most complex of organs, and serving as a resource for researchers around the world to study the interplay between these genetic programs and neurodevelopmental disorders such as autism, intellectual disability, and schizophrenia.

«The method thus opens up completely new opportunities for investigating disorders in the architecture of the developing human brain,» explains Dr. Julia Ladewig, who leads a working group on brain development.

It will also be interesting to investigate whether this protein is involved in other viruses, such as Rubella, that can also access and impair the developing human brain.»

The overlap between Zika cases in pregnant women and an increase in babies born with microcephaly strongly suggested that the virus targets stem cells in the developing human brain, but why and how has remained a mystery.

«The routine capture of single cells and accurate sampling of their molecular features now is possible,» said Alex Pollen, PhD, who along with fellow Kriegstein - lab postdoctoral fellow Tomasz Nowakowski, PhD, conducted the key experiments, in which they analyzed the activation of genes in 301 cells from across the developing human brain.

UC San Francisco researchers have identified cells» unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large - scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.

The study represents the first salvo of a larger BRAIN Initiative - funded project in Kriegstein's lab to understand the thousands of different cell types that occupy the developing human brain

Kriegstein's lab had already done extensive work characterizing the cells in the developing human brain, and when Alex Pollen, PhD, a postdoctoral fellow, read the previous Zika paper, he recognized the gene and started looking for which cells in the developing brain produce the receptor, making them theoretically vulnerable to Zika infection.

Strengthening the link between Zika virus and microcephaly, scientists at UC San Francisco have discovered that a protein the virus uses to infect skin cells and cause a rash is present also in stem cells of the developing human brain and retina.

Now researchers at UC San Francisco have taken the first step toward a comprehensive atlas of gene expression in cells across the developing human brain, making available new insights into how specific cells and gene networks contribute to building this most complex of organs, and serving as a resource for researchers around the world to study the interplay between these genetic programs and neurodevelopmental disorders such as autism, intellectual disability and schizophrenia.

UCSF scientists have discovered a new stem cell in the developing human brain.

A study published in May used fetal brain tissue to investigate how the Zika virus gains access to the developing human brain, where it can cause catastrophic birth defects.

October 18, 2011 Young human - specific genes correlated with brain evolution Young genes that appeared since the primate branch split from other mammal species are expressed in unique structures of the developing human brain, a new analysis finds.

Inappropriate hormone levels can have a devastating effect on the developing human brain, especially during the first 12 weeks of pregnancy when the fetus depends on the mother's thyroid hormones for brain development.

Neural correlates of socioeconomic status in the developing human brain.

Again, modern imaging methods are enabling this information to be translated to the developing human brain (27), and indeed, imaging with neuropsychology is an area where rapid progress is being made and needs to be made to translate the growing basic neuroscience knowledge of mechanisms into clinical relevance and application.

Quality of early care and buffering of neuroendocrine stress reactions: Potential effects on the developing human brain