Sentences with phrase «developing human monoclonal antibody»

«This panel of neutralizing antibodies offers the possibility of developing human monoclonal antibody - based immunotherapy, especially for health care workers,» noted the authors.

Not exact matches

Dupilumab, a fully human monoclonal antibody discovered by Regeneron Pharmaceuticals and being developed by Regeneron and Sanofi, thwarts activation of the Th2 immune response implicated in asthma by blocking two cytokines, interleukin - 4 and interleukin - 13.

The new inoculation series requires an injection of human or horse immunoglobulin, which is in short supply in developing countries, but the University of Massachusetts Medical School in Boston is currently testing a strategy in India that uses monoclonal antibodies that could one day be easily manufactured in China.

In the current study, Vanderbilt researchers led by graduate student Andrew Flyak, the paper's first author, used a high - efficiency method they developed to quickly isolate and generate large quantities of monoclonal human antibodies from the blood of survivors of a 2007 outbreak in Uganda who were infected by the Bundibugyo ebolavirus.

These mice also do not have intact immune systems: Humans might develop antibodies to the monoclonals, rendering them ineffective.

Investigators compared WR321, a non-human monoclonal IgG antibody that binds to phosphoinositide lipids, developed by Dr. Gary Matyas at MHRP, with a human monoclonal IgG antibody that in recent studies was found to have lipid - binding characteristics, including binding to phosphoinositides, but also bound to numerous other lipids.