Sentences with phrase «developing lung tumors»

The research could help determine which individuals are at greatest risk of developing lung tumors that may be amenable to a new therapy to inhibit their progression.

Mice that inhaled cumene fumes developed lung tumors and liver tumors, according to HHS's review.

Not exact matches

Paweletz and his colleagues are now developing a PCR - based test to detect drug resistance mutations in lung tumors.

A team of researchers, led by Ross Cagan, PhD, developed a multi-gene lung cancer model in the fruit fly Drosophila to better understand the mechanisms that promote tumors in NSCLC.

Similar to humans, the mice developed tumors at secondary sites including the liver, lung, peritoneum, and diaphragm.

Global Cancer Facts and Figures, 2nd Edition, a report released in 2011 by The American Cancer Society, notes that cancers related to changing lifestyles as nations become wealthier, including lung, breast, and colorectal tumors, continue to rise in the developing world http://www.cancer.org/Research/CancerFactsFigures/GlobalCancerFactsFigures/global-facts-figures-2nd-ed

By contrast, 16 out of 17 mice that produced annexin A2 in their cells developed metastatic tumors in the liver, lungs or abdominal cavity.

«We found that many more mice developed tumors when given the cells that we had engineered to have these stem cell characteristics, and they had a much higher incidence of metastasis in the lungs,» Kilian said.

The company is also developing techniques for analyzing other lung images, and images of cancerous tumors, to guide treatment using variations of the same technology.

To investigate why checkpoint inhibitors so often stop working, Velculescu; Valsamo Anagnostou, M.D., Ph.D., instructor of oncology at the Johns Hopkins University School of Medicine; Kellie N. Smith, Ph.D., a cancer immunology research associate at the Johns Hopkins University School of Medicine; and their colleagues at the Bloomberg ~ Kimmel Institute for Cancer Immunotherapy studied tumors of four patients with non-small cell lung cancer and one patient with head and neck cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-CTLA4.

Mice injected with breast cancer cells making lots of a long strand of RNA called HOTAIR developed 10 times as many lung tumors as controls (left) did.

In one, a liver and armpit tumor that had developed from spreading melanoma cells shrank, and in the other a lung tumor disappeared.

This mouse model develops primary mammary tumors that spontaneously metastasize to the lung (Guy et al., 1992; Lin et al., 2003).

An anti-PD-1 antibody developed by Bristol - Myers Squibb generates excitement with results from a phase I trial showing that, among 236 patients with various types of cancer, the treatment shrank tumors in 28 percent of melanoma patients, 30 percent of patients with kidney cancer, and 18 percent of patients with advanced non-small cell lung cancer.

Li - Fraumeni syndrome (LFS) is a genetic disorder associated with an increased risk of developing several forms of cancer, including soft tissue sarcoma, breast cancer, leukemia, lung cancer, brain tumors and adrenal gland tumors.

A tumor had developed in Jimmy's mastoid bone, pressing upon his brain, and the cancer spread to one lung.

It has a high incidence of spontaneous lung adenomas, and lung tumors readily develop in response to carcinogens.

The researchers used a modified virus to insert genetic mutations into cells lining the mice's lungs, causing the animals to develop tumors.

Cancer Institute research highlights include innovative studies to develop individualized approaches for treatment and prevention of lung cancer; collaboration between medical and materials science researchers to develop treatments for various types of leukemia using nanotechnology to target only cancer cells; and development of novel therapeutics to treat metastatic melanoma using an approach that regulates the processes leading to tumor development.

In patients who had their tumor removed by surgery but did not receive chemotherapy, 80 % developed new disease in the lungs and other bones.

The company's initial goal is to identify and deploy therapeutic neo-antigens from individual patients» tumors to develop novel treatments for lung cancer.

Her current focus is on developing clinical protocols for the treatment of head and neck and lung cancers with a goal of providing enhanced tumor control, including control of metastases, with minimal effect of quality of life.

Another recent grant, awarded to Sandra Gollnick, PhD, Director of the Photodynamic Therapy Center, Member of the Department of Cell Stress Biology and Distinguished Professor in the Department of Immunology, will enable the creation of an international registry compiling information about patients» responses to photodynamic therapy (PDT), an approach developed at Roswell Park that is now used in the treatment of many lung, esophageal, head and neck, pancreatic, and mesothelioma tumors.

Most secondary or metastatic tumors in cats develop in the lungs and, in contrast to women, rarely in bones.

Infections in humans do not completely develop, but may cause a lesion in the lungs «coin sign» that may be mistaken for a tumor.

Stage 1: Tiny tumors may develop within the lining of a lung.