Sentences with phrase «developing mechanistic»

Using this «Ribotag» approach tissue - specific changes under DR have been measured in muscle, fat, gut, heart, neurons, germline and malpighian tubules, showing a highly tissue specific response upon DR.. We are developing mechanistic models of gene expression regulation and conducting comprehensive bioinformatics analyses on UTRs, promoters and the coding sequences of various elements of differentially regulated genes.

Since scientists first decoded a draft of the human genome more than 15 years ago, many questions have lingered, two of which have been addressed in a major new study co-led by a Princeton University computer scientist: Is it possible, despite the complexity of billions of bits of genetic information and their variations between people, to develop a mechanistic model for how healthy bodies function?

The overall aim of my research is to develop a mechanistic understanding of the pathogenesis of accelerated cardiac and renal dysfunction during cardio - renal syndrome.

Woodburn, a hydrogeologist by training, along with Carl Steefel, head of Berkeley Lab's Geochemistry Department, will develop a mechanistic numerical model of the Cosumnes River watershed, which extends from the Sierra Nevada to south of Sacramento, ultimately feeding into the Sacramento - San Joaquin River Delta and the California State Water Project, the major source of water for much of Southern California.

Not exact matches

My point here is that evolutionary theory, developed in the context of a mechanistic worldview, was a real threat to faith.

A second response was to develop a different worldview in which Christians could both affirm the empirical evidence for evolution and deny that it has the reductionistic implications given it by the mechanistic worldview.

In the 19th century mechanistic physics developed into a rational determinism, Darwin contradicted not only the Bible but also Aristotelian natures, which, known through abstraction, should remain always the same.

«This is really the first time we've gone from risk variants highlighted by GWAS to a mechanistic and molecular understanding — right down to the nucleotide — of how a mutation can contribute to the risk of developing disease,» says Whitehead Founding Member Rudolf Jaenisch, who is also a professor of biology at MIT.

«Mechanistic finding may help develop treatment for Ice Bucket Challenge disease: Study blames a fault in the cell's machine that cuts and pastes genetic instructions for a deadly motor neuron disease.»

A mechanistic understanding of bleaching is critical for developing strategies to mitigate or eliminate the problem of coral decline.

«A mechanistic understanding of how plants resist or overcome pathogen attack is crucial to develop new strategies for crop protection.»

Although the AOPs developed until now have addressed chemical toxicity, the approach also lends itself to describing the mechanistic basis to potential adverse effects caused by nanomaterials, as demonstrated very recently by the JRC.

The AOP framework has been developed through an extensive international collaboration between scientists, regulators and policy - makers with the primary goal of making mechanistic toxicological knowledge more readily available to support safety assessment decisions.

In addition, he adds, the research is part of «figuring out very mechanistic descriptions of how attention works,» which can be used in the future «to develop better tools and better objective measures for diagnosing disorders like ADD and dyslexia.»

Thus, we will develop additional mouse models in both areas, will design and use further molecular assays, to address functional and mechanistic problems.

The objective is to create transforming technologies, explain mechanistic forces, and develop theoretical frameworks to analyze, predict, and ultimately understand microbial communities.

The successful candidate will provide expertise to assess the human safety of Unilever ingredients within multidisciplinary teams developing & applying novel, mechanistic / pathways based approaches.

Based on this information, the team developed a conceptual mechanistic model for how uraninite would react in groundwater.

In light of these realizations, the long - term scientific goal of the program is to develop a detailed and mechanistic understanding of not just the tumor cell and tumor mutations, but also all the components of the host microenvironment that influence cancer and the response to cancer therapy.

From these cell based and clinical studies, we have developed important mechanistic ideas such as activation of protein kinase C, the role of vascular endothelial growth factor (VEGF) and selective insulin resistance as some of the basic mechanisms for the pathogenesis of diabetic microvascular and cardiovascular diseases which are now widely studied by multiple laboratories.

The ultimate goal of this line of investigation is to leverage these newly gained mechanistic insights for developing new therapeutics in a personalized manner based on one's unique genetic and / or pathway signatures.

Dr. Cole's project, «Mechanistic Derivation of Germ Line Mutation by Genome - Wide Mouse Tetrad Analysis,» will help define the global patterns of de novo germ line mutations and the frequencies at which such mutations occur in mice, with the long term goal of understanding the molecular mechanisms underlying germ line mutagenesis and developing strategies to prevent or treat disorders caused by such mutations.

Dr. Wang's research interest is in developing ab initio electronic structure calculation methods and applying these methods to material design, discovery, and mechanistic understanding.

In that regard, maybe this «Helping Individuals to Understand Synergistic Risks: An Assessment of Message Contents Depicting Mechanistic and Probabilistic Concepts» could help develop the necessary skills to comprehend what's actually being said about agw / cc impacts into the future especially +2100 and the reality of the present global trajectory?