Sentences with phrase «developing nanoparticles»

There, Stephan began developing nanoparticles able to convey anything from new genes to immune - stimulating factors to T cells inside patients.

For the past two decades, scientists have been developing nanoparticles made from a broad range of materials and adding compounds such as cholesterol to help carry these therapeutic agents into cells.

All the interdisciplinary skills and knowledge he had gathered during his scientific training — which had covered biochemistry, biotechnology, biomaterials, and stem cell biology — put him «in a very advantageous position to address this question» of how to develop nanoparticles that could modulate stem cell differentiation on demand, he says.

To find a way to deliver siRNAs for curbing FL2, Dr. Sharp collaborated with Joel Friedman, M.D., Ph.D., professor of physiology & biophysics and of medicine at Einstein, and study co-leader Adam Friedman, M.D., director of dermatologic research at Einstein and Montefiore, who together had developed nanoparticles that protect molecules such as siRNA from being degraded as they ferry the molecules to their intended targets.

Shukla hopes to further develop the nanoparticles to work against HIV, which like HSV - 2 also has positively charged proteins embedded in its outer envelope.

Selecta has developed a nanoparticle delivery system in which an immune - modifying compound is contained in biodegradable plastic particles just 150 nanometres across.

Anderson and Langer have previously developed nanoparticles, now in clinical development, that can deliver siRNA to liver cells called hepatocytes by coating the nucleic acids in fatty materials called lipidoids.

INM will be demonstrating flexible touch screens, which are produced by printing recently developed nanoparticle inks on thin plastic foils.

To bypass these limitations, Sunday Shoyele, PhD, Associate Professor in the Department of Pharmaceutical Sciences at Jefferson (Philadelphia University + Thomas Jefferson University) and colleagues, developed a nanoparticle comprised of four parts.

In a new study, MIT researchers have developed nanoparticles that can deliver the CRISPR geno... Read more

Penn State College of Medicine researchers have developed a nanoparticle to deliver a melanoma - fighting drug directly to the cancer.

Now, a team of scientists from the Helmholtz Zentrum München (HMGU) and the Ludwig - Maximilians - Universität (LMU) in Munich have developed a nanoparticle aimed at destroying cancerous tissue in the lungs.

Researchers at BWH developed the nanoparticles using biodegradable, FDA - approved polymers engineered to carry the healing, stabilizing anti-inflammatory peptides.

A newly developed nanoparticle may signal the end of injections for treatment of some common diseases (Image: Christine Daniloff)

Not exact matches

Cambridge, MA — February 6, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that the U.S. Food and Drug Administration (FDA) has cleared the investigational new drug application (IND) for the company's lead program, light - activated AU - 011 in ocular melanoma (OM).

Cambridge, MA — December 21, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it closed a $ 30 million Series C financing.

Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the treatment of ocular melanoma, a rare and life - threatening disease.

Researchers have developed a technique for using polymer - based nanoparticles to dissolve infectious bacteria's protective outer membranes so they can not morph into more dangerous forms

So they developed a drug that inactivates the gene that makes FL2 and then put the drug in tiny gel capsules called nanoparticles and applied the nanoparticles to wounds on mice.

For this study, Yanik's team developed a new technology to inject RNA carried by nanoparticles called lipidoids, previously designed by Daniel Anderson, an associate professor of chemical engineering, member of the Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science, and an author of the new paper.

VTT Technical Research Centre of Finland and Tampere University of Technology (TUT) have developed a comparison technique which has detected marked differences between the nanoparticle - capturing performance of air filters.

Huang and his co-workers have developed such windows by coating glass with tin oxide nanoparticles doped with small amounts of the element antimony.

Now, in a new study using laboratory - grown cells and mice, Johns Hopkins scientists report that a method they used to track metabolic pathways heavily favored by cancer cells provides scientific evidence for combining anti-cancer drugs, including one in a nanoparticle format developed at Johns Hopkins, that specifically target those pathways.

Future studies will be required to test whether the antibody levels prevent dengue infection as well as whether similar nanoparticles can be develop for all dengue serotypes.

Arnd Pralle, a physics researcher at the State University of New York at Buffalo, has developed a technique for employing magnetic fields to heat up nanoparticles that have been implanted in neurons.

With this in mind, scientists from the Center for Nanomedicine at Johns Hopkins, led by Hanes, encapsulated the BPTES in a nanoparticle capsule coated in polyethylene glycol, a molecule used widely in medicines and industrial products, using a method they developed to provide a more uniform coating.

ZOTEN nanoparticles were synthesized using technology developed by material scientists at Germany's Kiel University and protected under a joint patent with UIC.

Cleaning oil spills could be as easy as scraping frosting off a cake, thanks to a nanoparticle coating developed by Philip Brown and Bharat Bhushan, engineers at the Ohio State University.

IBM developed a technique for making carbon nanotubes emit light, paving the way for new fiber optics; Harvard scientists figured out how to deposit tiny wires on glass or plastic, opening the door for the development of supercheap computers; and at the University of Central Florida, neuroscientist Beverly Rzigalinski discovered a nanomolecular fountain of youth effect: When Rzigalinski applied cerium oxide nanoparticles to rat neurons in a petri dish, the particles seemed to strip out the free radicals that make tissues age and kept the neurons alive and functioning up to six times their normal life span.

«I am so happy that more of these types of nanoparticle - based hyperthermal therapies are being developed to increase the arsenal of weapons against cancer.»

The technology, developed by MIT professor and Howard Hughes Medical Institute investigator Sangeeta Bhatia, relies on nanoparticles that interact with tumor proteins called proteases, each of which can trigger release of hundreds of biomarkers that are then easily detectable in a patient's urine.

The researchers developed a small, breath - diagnostic array based on flexible gold - nanoparticle sensors for use in an «electronic nose.»

The nanoparticles, developed by Langer, seemed a safer option.

In the new study, Anderson and colleagues developed a combined nanoparticle and viral delivery system to deliver the CRISPR repair machinery.

Moving to an animal model, they applied the nanoparticles and hydrogen peroxide topically to the teeth of rats, which can develop tooth decay when infected with S. mutans just as humans do.

A team of researchers, led by Sangeeta Bhatia, an associate professor at HST and in M.I.T.'s department of electrical engineering and computer science, report in Advanced Materials that they have developed and tested injectable multifunctional nanoparticles — particles billionths of a meter in size — that they expect to become a new, potent weapon against cancer.

In earlier work, the researchers developed a virus - killing nanoparticle coated in the sugar that the influenza virus uses to invade lung tissue.

There is an expanding array of nanoparticle types being developed and tested for cancer therapy.

The researchers found that it was possible to combine the gel with silica nanoparticles — microscopic particles previously found to stop bleeding — to develop an even more powerful barrier to promote wound healing.

Scientists at the U.S. Naval Research Laboratory (NRL) Materials Science and Technology Division have developed a novel one - step process using, for the first time in these types of syntheses, potassium superoxide (KO2) to rapidly form oxide nanoparticles from simple salt solutions in water.

«We have been developing the expertise required to grow intricate core / shell and other well defined nanoparticles for many years,» Vela said, «Through our collaboration with Emily Smith's group, we hope to continue making inroads in our ability to manipulate and direct energy flows at the nanoscale.»

To develop subunit vaccines for other diseases, scientists have tried targeting them to lymph nodes using nanoparticles to deliver them, or tagging them with antibodies specific to immune cells in the lymph nodes.

To achieve gene editing in mice with thalassemia, professor of therapeutic radiology and of genetics Peter M. Glazer, M.D. and his co-authors developed an alternative approach using a novel combination of nanoparticles, synthetic pieces of DNA, and a simple IV injection.

«The new optically active nanoparticle we have developed is able both to achieve tumor photodamage and to suppress multiple escape pathways, opening new possibilities for synchronized multidrug combination therapies and tumor - focused drug release.»

The researchers developed a drug carrier that consists of polymeric nanoparticles coated with specialized antibodies that target a small conserved (i.e., invariable) part of the parasite surface.

Although this method was developed with upconversion nanoparticles, the researchers believe their new «direct - doping» approach can be generalised to other nanoparticles with interesting photonic, electronic and magnetic properties.

By tweaking the size of the rhodium nanoparticles, they also hope to develop a version of the catalyst that is powered by sunlight, creating a solar - powered reaction that could be integrated into renewable energy systems.

The researchers also developed a method of delivering the PNA / DNA via microscopic nanoparticles.

Duke University researchers have developed tiny nanoparticles that help convert carbon dioxide into methane using only ultraviolet light as an energy source.

VTT Technical Research Centre of Finland Ltd has developed a new, cost - efficient method of producing various types of metallic nanoparticles.