Palm alerted Swedish health authorities, and subsequent population - wide studies in Sweden, Finland, Ireland and the United Kingdom suggested that vaccination for H1N1 — but only with the Pandemrix vaccine — had increased the risk of
developing narcolepsy between four - and 13-fold in children and adolescents, and between two - and four-fold in adults.
► Why did about 15,000 children in Europe
develop narcolepsy after receiving the flu vaccine Pandemrix?
Researchers suspect an autoimmune reaction is to blame because many people who
develop narcolepsy — and just about everyone with the vaccine - associated form — have a specific variant in a gene in the HLA family, which helps the body distinguish its own proteins from those made by microbial invaders.
Studies of genetically identical twins have shown that when one twin
develops narcolepsy, the other tends not to.
He developed narcolepsy as a result of the tumor, a pre-existing condition that sent his health costs skyrocketing.
Not exact matches
Take the Air Force's 2004 approval of Modafinil, a drug first
developed to treat
narcolepsy, the chronic sleep disorder, for its pilots.
Exploiting methods that he
developed in his hunt for the gene responsible for
narcolepsy, Mignot is now in hot pursuit of a KLS gene.
Modafinil,
developed for people with
narcolepsy, is now a drug of choice for those who want to burn the midnight oil.
And it may be that the vaccine only accelerated progression of
narcolepsy in children who would have
developed it anyway.