Sentences with phrase «developing new targeted therapy»
The molecular pathways underlying some of the most prevalent and deadly types of cancer, to develop new targeted therapies and move forward in the direction of personalized cancer treatment
https://wistar.org/ Not exact matches
Cambridge, MA — February 6, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that the U.S. Food and Drug Administration (FDA) has cleared the investigational new drug application (IND) for the company's lead program, light - activated AU - 011 in ocular melanoma (OM).
Cambridge, MA — December 21, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it closed a $ 30 million Series C financing.
Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the treatment of ocular melanoma, a rare and life - threatening disease.
Researchers at New York University College of Dentistry (NYU Dentistry) have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetNew York University College of Dentistry (NYU Dentistry) have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetnew target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.
«It is expected that this study will lay the foundation for developing a new class of potent and effective cancer therapies and the development of reagents targeting epigenetic events in immune - mediated diseases as well as other epigenetically - influenced diseases,» said Alani, who also is chief of dermatology at Boston Medical Center.
«This is a seminal step in identifying key pathways and molecules involved in kidney cancer so that specific therapies that target these new genes can be developed to treat this cancer.»
With the data provided by the FLI researchers, scientists around the world may now set targeted mutations to investigate the relevance of single genes for aging, in order to better understand regulating mechanisms and, eventually, develop new approaches for therapy or prevention of aging - related diseases.
In cases of new infection, prompt and targeted therapy is vital, as it can prevent the disease developing into a chronic condition that can lead to inoperable liver cancer.
By tracking and understanding which host cell pathways are manipulated by these T. gondii proteins, scientists can identify potential new targets to develop more effective therapies against highly aggressive solid tumors.
New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapiNew research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapinew cancer therapies.
Identifying microbiota - derived metabolites and understanding their effects on specific host functions could open up new avenues of basic and clinical research to develop safe, targeted therapies involving molecules that, by definition, constitute the natural chemical makeup of the host.
Thus, finding new targets for drugs already in use to treat other diseases, in other words drug repurposing, is an emerging area in developing anti-cancer therapies.
Nevertheless, trying to develop new therapies based on what treatments will look like in the coming decade is a nearly impossible task, points out Michael Stratton, joint head of the Cancer Genome Project and professor of cancer genetics at the University of London's Institute of Cancer Research, who has been working on developing finely targeted cancer treatments since identifying the BRAF oncogene in 2002.
«Our findings may not only help to understand the causes of depression, but also may provide a new biochemical target for developing more effective therapies.»
«At Exeter we are already developing specific psychological therapies, running clinical trials of novel drug approaches and using - cutting edge genetic techniques to identify new targets for safe and effective therapies and to allow us to use current treatments in a more focussed way.»
This work shows that the tumor microenvironment itself can compromise the efficacy of targeted therapies and should be taken into account as new treatment approaches are developed.»
The field has experienced monumental challenges developing new and effective drug therapies, not the least of which was the discovery that — until recently - clinical trials were conducted where up to 30 % of participants did not have the Alzheimer's disease - related brain change targeted by the experimental drug.
Where research uncovers possible mechanisms for disease, those working in drug discovery can use these data to develop novel diagnostic or monitoring tools, to develop therapies that address the biological pathways concerned, or to develop companion diagnostics to ensure that new — or existing — therapies are targeted at the correct subgroup of patients.
NIH Funds Scripps Research - Novartis Collaboration to Target New Treatments for Depression and Nicotine Addiction A $ 3.45 million grant has been awarded to a group of researchers from The Scripps Research Institute and Novartis Pharma AG to develop new therapies for depression and nicotine addictiNew Treatments for Depression and Nicotine Addiction A $ 3.45 million grant has been awarded to a group of researchers from The Scripps Research Institute and Novartis Pharma AG to develop new therapies for depression and nicotine addictinew therapies for depression and nicotine addiction.
In a relatively new but rapidly expanding field of study, researchers aim to decipher which of these microbial players are key to certain diseases, and which can be targeted to develop new therapies for patients.
Leveraging highly automated process engineering and personal scale biologics manufacturing, Affigen develops new therapies for previously «undruggable» targets.
«Part of our work is designed to help us understand what new therapies we can develop, and part of it is to help us understand how to target existing therapies.»
The ultimate goal is to increase the number of new diagnostics and therapies for patients while reducing the time and cost of developing them, by jointly identifying and validating promising biological targets for several diseases, including type 2 diabetes.
New research findings from The University of Texas at Dallas unveil how kidneys filter ultra-small engineered particles, which may lead to new ways of developing targeted therapy for the detection and treatment of kidneyNew research findings from The University of Texas at Dallas unveil how kidneys filter ultra-small engineered particles, which may lead to new ways of developing targeted therapy for the detection and treatment of kidneynew ways of developing targeted therapy for the detection and treatment of kidney...
This will fast - track new immune - modulating therapies for cancer patients by discovering and developing small molecule product candidates against immuno - oncology targets.
My background was in the identification of drug targets in prostate cancer, so working on developing new therapies in glaucoma was a natural progression.
To this end, she continues research to understand how blood proteins harm the brain and to develop new therapies that target these proteins.
The idea there is that by identifying genes that cause, or contribute to glaucoma, and understanding what the protein products of those genes do, we can use new techniques to target those proteins to develop therapies that actually approach the actual disease mechanisms that cause the disease.
The goal of this Center of Excellence is to better understand the mechanisms of vascular dysfunction that lead to PVD, including the various forms of PAH, and to develop new targets and strategies for individualized therapies.
Right now all therapy for glaucoma is directed at lowering eye pressure, but the idea that we could develop therapies and test them in people that really target the retinal ganglion cells and the axon fibers going into the optic nerve — that, I think, is the most exciting new frontier for the premise of restoring vision and protecting vision in glaucoma.
Newer lines of research are focused on understanding cancer stem (CSC) cell biology so that therapies targeting them can be developed.
• Determine types of therapies required for each child and develop specific therapeutic treatment plans to meet his or her individual needs • Handle assessments by interviewing and observing children and creating psychological profiles • Create new programs, move targets forward and make procedural changes in existing care / educational programs • Lead special education trainings and plan and implement staff development and patient education autism programs • Confer and communicate with staff members to gauge the effectiveness of special education programs
When you join me in therapy, we will develop a therapy plan, that will introduce you to new strategies, targeted at meeting your specific goals.»
This article describes a new model, TARGET (Trauma Affect Regulation: Guide for Education and Therapy), that was developed and has been tested with justice - involved youth, and that has been disseminated in several state - wide juvenile justice systems.