Sentences with phrase «development against the virus»
The findings are published this week in the Proceedings of the National Academy of Sciences (PNAS) and provide the foundation for future antiviral drug and vaccine development against the virus, rhinovirus C.
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That development is important because a T cell response will likely confer longer - term protection than current inoculations do and defend against a variety of flu strains (because T cells would be on the lookout for several different features of the flu virus whereas antibodies would be primarily focused on the shape of a specific strain).
We are making efforts to apply these findings in the development of drugs against viruses such as human parainfluenza virus,» Professor Sakaguchi described.
Just over a year ago, the same team of South African researchers reported in Nature Medicine (also part of the Nature group of journals) on their discovery relating to two other KwaZulu - Natal women, that a shift in the position of one sugar molecule on the surface of the virus led to the development of broadly neutralizing antibodies against HIV.
Thus these plant extracts may be useful starting material for the development of potent herbal agents against selected virus infections.
The first live - attenuated Zika vaccine still in the development stage completely protected mice against the virus after a single vaccination dose, according to new research from The University of Texas Medical Branch at Galveston and Instituto Evandro Chagas at the Ministry of Health in Brazil.
This small molecule is in clinical trials against cancer and has high specificity and good pharmacological properties, which could warrant its further development as antiviral drug for treatment of pH1N1 virus infection,» Dr. Oxana Denisova says.
«Drugs approved to treat hepatitis C and compounds in development to treat other viral diseases are prime candidates to use against the Zika virus,» Kao said.
«As such, the development of effective countermeasures against these viruses is a critical need.»
«The discovery of novel intracellular receptors for viruses, like LAMP1 for Lassa virus, opens the door for the development of therapeutics directed against these previously unknown targets,» said Dye.
A major goal of HIV - 1 vaccine development is to identify immunogens capable of inducing protective titers of broadly neutralizing antibodies (bNAbs) against circulating, neutralization - resistant (tier 2) viruses.
«As eliciting a highly diverse immune response may be favorable to providing protection against incredibly diverse HIV - 1 variants in global circulation,» the researchers conclude that their study «supports further investigations of the molecular and functional characteristics of the virus - antibody interplay in superinfected individuals, as superinfection may provide insight to the development of a diverse Nab response with multiple epitope specificities.»
The structure could inform vaccine development, as the Zika E glycoprotein is a key target of immune responses against the virus.
In conclusion, the antibodies characterized herein show promise for development as broadly reactive therapeutic agents against the pandemic H1N1 influenza virus, as well as against the majority of H1N1 and H5N1 influenza strains.
Dr Peter Barlow says study represents a promising step forward in the rapid development of a safe and robust vaccine against Zika virus infection in humans.
We have completed the active phase of a Phase 1 trial of a Vaxwave ® - based vaccine against cytomegalovirus (CMV) and are finalizing clinical development plans for TheraT ® in Human Papilloma Virus (HPV)- related head and neck cancers.
«It also was effective against known drug - resistant strains of the HIV virus, making it a very promising candidate for further development into a new HIV drug.»
«These findings certainly raise optimism that the development of a safe and effective vaccine against Zika virus for humans may be successful,» he said.
The chronically stressed mice had decreased immune function and experienced tumor development significantly earlier than the non-stressed mice.16 Other mouse studies of ovarian cancer showed that chronic stress resulted in increased cancer growth as well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risk.
Additional Foundation - funded studies helped lay the groundwork for the development of the first vaccine against feline leukemia virus.
development of a novel vaccine strategy against feline enteric coronavirus, the nonlethal virus that can mutate into the FIP virus
In human medicine, our growing knowledge about the role of viruses as a cause of certain cancers has led to the development of vaccines as preventives, such as vaccines against human papillomaviruses, the main cause of cervical cancer in women.
«Helping fund the development of the rapid diagnostic tool is just one way we are investing in and are committed to finding a solution against this virus,» said Gloria Basse, Vice President, U.S. Pork Business Unit, Zoetis.
Potential new agents are also being investigated that it is hoped will overcome limitations of the current options, which include a narrow antiviral spectrum, ineffectiveness against latent virus infections, development of drug - resistance and toxic side effects.