Sentences with phrase «development by arthritis»

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That suggests that this sodium channel could be a target for the development of drugs to prevent the pain caused by acid build - up — which happens in arthritis and other inflammatory disorders.

To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.

Environmental factors are thought to play a role in the development of rheumatoid arthritis by triggering autoimmune reactions in susceptible individuals.

Their work was funded by several NIH components, including the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and National Institute on Aging (NIA).

The research was funded by the National Institute of Child Health and Development, the National Institute of Diabetes, Digestive and Kidney Disorders, the National Institute for Arthritis and Musculoskeletal Disorders, the German Academic Exchange Service, and the Medical Research Council.

This, in turn, sets the stage for the development of autoimmune diseases like rheumatoid arthritis or lupus, 2 Cordain, L., Toohey, L., Smith, MJ., et al. «Modulation of immune function by dietary lectins in rheumatoid arthritis,» The British Journal of... continue and creates chronic inflammation throughout your body.

Although overweight and other factors can contribute to osteoarthritis, a main factor in the development of this most common by far type of arthritis seems to be especially the poor blood circulation in capillaries (the smallest blood vessels) which are responsible for delivering nutrients and oxygen to the joints.

These changes are important because both stressors and depression can sensitize the inflammatory response in such a way that they produce heightened responsiveness to stressful events as well as antigen challenge.25, 27,28,60 Furthermore, more frequent or persistent stress - related changes in plasma levels of these key cytokines have broad implications for health; elevated levels of proinflammatory cytokines have been linked to a variety of age - related disease, including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes mellitus, certain cancers, and frailty and functional decline.29 Moreover, inflammatory activation can enhance development of depressive symptoms.30, 31 Thus, relationships characterized by hostility, repeated conflicts, and heightened IL - 6 levels could have negative consequences for both physical and mental health.