Sentences with phrase «development by controlling»

We thus assess the role of environmental influences on cognitive development by controlling for indicators of living conditions in our analysis.

GPCRs and their downstream signaling are involved in cancer growth and development by controlling many features of tumorigenesis, including immune cell - mediated functions, proliferation, invasion and survival at the secondary site.

One of the «hits» was Lhx1, a member of a family of genes whose protein products affect development by controlling the activity of other genes.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

By using its own processors, the company would have finer control over product development and would be able to better tune its software and hardware together.

Among the factors that could cause actual results to differ materially are the following: (1) worldwide economic, political, and capital markets conditions and other factors beyond the Company's control, including natural and other disasters or climate change affecting the operations of the Company or its customers and suppliers; (2) the Company's credit ratings and its cost of capital; (3) competitive conditions and customer preferences; (4) foreign currency exchange rates and fluctuations in those rates; (5) the timing and market acceptance of new product offerings; (6) the availability and cost of purchased components, compounds, raw materials and energy (including oil and natural gas and their derivatives) due to shortages, increased demand or supply interruptions (including those caused by natural and other disasters and other events); (7) the impact of acquisitions, strategic alliances, divestitures, and other unusual events resulting from portfolio management actions and other evolving business strategies, and possible organizational restructuring; (8) generating fewer productivity improvements than estimated; (9) unanticipated problems or delays with the phased implementation of a global enterprise resource planning (ERP) system, or security breaches and other disruptions to the Company's information technology infrastructure; (10) financial market risks that may affect the Company's funding obligations under defined benefit pension and postretirement plans; and (11) legal proceedings, including significant developments that could occur in the legal and regulatory proceedings described in the Company's Annual Report on Form 10 - K for the year ended Dec. 31, 2017, and any subsequent quarterly reports on Form 10 - Q (the «Reports»).

The RIC's most recent advance, the development of the world's first mind controlled prosthetic leg, was aided by $ 8 million worth of funding from the U.S. Army's Telemedicine and Advanced Technology Research Center.

As clearly demonstrated by developments of the last two years, you do not have control over budgetary revenues, cyclically sensitive spending, such as unemployment insurance benefits, and public debt charges.

However, attempting to hit a single year deficit / surplus target is extremely difficult, as it is influenced by many factors outside the control of the government, most notably by economic developments.

A company controlled by Miami investor Ricardo Caporal paid $ 5 million for a development site near Miami's Westchester neighborhood, property records show.

This will be determined by international developments — factors beyond the government's control.

Not later than 270 days after the date of enactment of the Dodd - Frank Wall Street Reform and Consumer Protection Act, the Commission shall issue final rules that require each resource extraction issuer to include in an annual report of the resource extraction issuer information relating to any payment made by the resource extraction issuer, a subsidiary of the resource extraction issuer, or an entity under the control of the resource extraction issuer to a foreign government or the Federal Government for the purpose of the commercial development of oil, natural gas, or minerals...

Factors that could cause actual results to differ materially from those expressed or implied in any forward - looking statements include, but are not limited to: changes in consumer discretionary spending; our eCommerce platform not producing the anticipated benefits within the expected time - frame or at all; the streamlining of the Company's vendor base and execution of the Company's new merchandising strategy not producing the anticipated benefits within the expected time - frame or at all; the amount that we invest in strategic transactions and the timing and success of those investments; the integration of strategic acquisitions being more difficult, time - consuming, or costly than expected; inventory turn; changes in the competitive market and competition amongst retailers; changes in consumer demand or shopping patterns and our ability to identify new trends and have the right trending products in our stores and on our website; changes in existing tax, labor and other laws and regulations, including those changing tax rates and imposing new taxes and surcharges; limitations on the availability of attractive retail store sites; omni - channel growth; unauthorized disclosure of sensitive or confidential customer information; risks relating to our private brand offerings and new retail concepts; disruptions with our eCommerce platform, including issues caused by high volumes of users or transactions, or our information systems; factors affecting our vendors, including supply chain and currency risks; talent needs and the loss of Edward W. Stack, our Chairman and Chief Executive Officer; developments with sports leagues, professional athletes or sports superstars; weather - related disruptions and seasonality of our business; and risks associated with being a controlled company.

And the Chinese development bank said it had changed its mind about lending to the CP Group, controlled by Dhanin Chearavanont, reportedly Thailand's richest man.

In the realms of both cultural development and technical innovation, ignorance and inflexibility are the enemy; Giancarlo stresses that the upcoming generation «see virtual currency — along with social media — as a means to bypass control by a failed generation of leadership.»

In the face of technical developments, which long ago made local and international radio - telephony possible, and which constantly opened up new wavebands for television — in the UHF band alone, the dissemination of numerous programs in one locality is possible without interference, not to mention the possibilities offered by wired and satellite television — the prevailing laws for control of the air are anachronistic.

Terrorism and torture tend to occur most where governments are not restrained by a democratically authorized constitution, where legal systems have little independence from military control, and where state authorities understand themselves to be the sole guarantors of order, development and stability.

It is neither possible nor desirable to question the development of international exchange, but it is necessary, by contrast, to bring about international co-operation to control the international operators and sanction practices which are contrary to national interests, particularly those of developing countries.

It does not allow any development other than that one which is fully or maximally controlled by the triad.

Religion was necessary in the development of human evolution to control violence by imputing guilt onto the scapegoat.

The internet allows parish musicians to take ownership of their development, unfettered by redundant and exclusive structures, which hark back to a more restricting and controlling age, long before the arrival of instant communication and clear accountability.

II, p. 241) At the stage of development represented by such an attitude, the value of religion was measured by the control given the devotee over superhuman powers and, so far as prayer was used, its object was to persuade a god to do the bidding of a man.

The new datum in our time is the development by molecular biologists of procedures which make it possible to control this recombining process (so that it is not simply «random»), and to increase almost immeasurably the speed by which it takes place.

means that these financial fountain springs has no planed directions or control over them to serve towards the developments of the Ranks and reducing gap between them by investing in a total su - sta - in - able development of all those ranks as to morals, knowledge, skills and their personal business investments.

At an early point in its development, this sense of God as in total control expressed itself and was reinforced by the affirmation of creation out of nothing.

If there are greater and more inclusive goods than wealth, then we should move toward what Friedman does not want — either the recovery of control of the market by national governments, or the development of a global government capable of establishing the parameters of market activity.

, is their historicity, their having been shaped by and their having some control over the process of historical change and development,» then we must attribute this element of self - reflexivity to the Paraiyars.

It may therefore be tested and controlled by a careful and critical study of the documents which caught and fixed it at the earliest accessible stage in its development.

What Max Weber saw in the sequence of Protestant developments was a remarkably different way to «ease tension» between religion and politics: «inner - worldly asceticism can compromise with the facts of the political power structures by interpreting them as instruments for the rationalized ethica1 transformation of the world and for the control of sin.

I do not know of any success stories in development where ownership and control of investments is by transnational corporations whose natural and appropriate interest is their own profits.

In the broad development of the biblical wisdom tradition, the pattern of wisdom, thus early made indigenous, continued by and large to shape and control its continuing expression.

In the Union of South Africa, where the government has limited the access in the black townships to FM radio (which covers a small area and can be controlled by the government), the development of small local newspapers has been one of the few ways black citizens can «talk» to one another.

The success of the Democratic coalition will be determined by events that are out of the easy control of any elected official, namely the ability of center - left political elites to work together effectively, and the ability of the center - right to adjust to the realities of present - day America (to say nothing of the course of the economy and developments in foreign countries).

KC: Having followed the technological growth model steered by elite controlled planning and programming, serious questions arise now about an alternative model of development.

Thus, the development of what products we are able to purchase and use to control the amount of information we access and digest is ultimately controlled by sources outside our household.

In Nazi Germany, scientific development was considerably weakened in a dozen years by political control of universities and laboratories and the promotion of «Aryan science.»

Of all the imported currents of the period, Protestantism was the exception to the rule, in that it was introduced (and, in its initial development, controlled) by foreigners.

The company prides itself on continuous innovation and its product development team is led by industry veteran Stacy Woodward, Florida Caribbean Distillers» director of quality assurance / control and product development for 25 years.

Although the expansion does stray from the company's concentric growth model, Parmerlee says the Asian development initiative is very much controlled by Tharp's separate team.

These developments might be enabled by improved quality control, fast changeover, greener production lines, and minimised contamination risks.108 Adoption and development of world - class technologies and analytical instruments will help keep Australian industry globally competitive.

The latest developments and innovations in food safety and quality control will be showcased in a special event being organised by packaging systems specialist Ishida Europe.

WebCenter 18 streamlines and speeds up the packaging development workflow by delivering extra features that give brand owners and converters more control and visibility over their packaging preproduction specification, approval and project life cycle.

This video provides recommendations on how to control weedy rice, from results of collaborative research studies among IRRI, the Rice Research and Development Institute in Sri Lanka, University of Ruhuna, and the Irrigated Rice Research Consortium funded by the Swiss Agency for Development and Cooperation.

WebCenter 18 streamlines and speeds up the packaging development workflow by delivering extra features that give brand owners and converters more control.

Ms Davies said the development brought to at least 30 the number of wine businesses impacted by the widening control zone.

As a result, developments in freezing technology in recent years have mostly been characterized by the improvements in mechanical handling and process control to increase freezing rate and reduce cost (George, 1993).

On a cognitive level, growing up in a chaotic and unstable environment — and experiencing the chronic elevated stress that such an environment produces — disrupts the development of a set of skills, controlled by the prefrontal cortex, known as executive functions: higher - order mental abilities that some researchers compare to a team of air - traffic controllers overseeing the working of the brain.

Because children spend so many hours each week at the Educare center, beginning at such an early age, the program has, more or less by default, a significant amount of control over their development up until their fifth birthday.

The proposal by Sen. Robert Menendez and Rep. Bill Pascrell involves national concussion guidelines currently under development for schools and youth sport programs by the U.S. Centers for Disease Control and Prevention.

Though the restaurant sits on the one part of Millennium Park still controlled by the Park District, the city argues that the Park District gave up development of that area of the park.