Sentences with phrase «development of blood vessels»
-- The symptoms result from an excess of the growth factor PDGF, which prevents the temporary blood vessels of the foetal stage from disappearing, which in turn prevents normal development of blood vessels in the retina, says Karin Forsberg Nilsson, professor at the Department of Immunology, Genetics and Pathology at the Rudbeck Laboratory, who directed the study.
http://www.scilifelab.se/
They are a good source of potassium, which may decrease the growth and development of blood vessel plaques and is also good for lowering high blood pressure.
They are a good source of potassium, which may decrease the growth and development of blood vessel plaques and is also good for lowering high blood pressure.
Not exact matches
But they also seem to inhibit the development of the fatty plaques that can clog up blood vessels and cause strokes.
One of the hallmarks of rheumatoid arthritis is the development of new blood vessels, or angiogenesis, in the joints.
An experimental drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).
Understanding this new mechanism of cardiovascular disease could lead to the development of new therapies to treat individuals who suffer from heart and blood vessel ailments due to these mutations,» explained corresponding author Kenneth Walsh, PhD, professor of medicine at BUSM.
In healthy blood vessels, more common in younger women, estrogen can slow the development of artery - clogging plaques.
Oxidative stress, inflammation and insulin resistance affect the inner linings of blood vessels, and are associated with the development of atherosclerosis, the disease process that underlies heart disease and causes the arteries to become narrowed.
Scientists from Trinity College Dublin and the Royal College of Surgeons in Ireland (RCSI) have discovered that abnormalities of blood vessels in the brain may play a major role in the development of schizophrenia, a debilitating condition that affects around 1 % of people in Ireland.
Because HIF signals cells to produce VEGF, the researchers wondered whether deleting HIF in amacrine and horizontal cells would also stop the pipeline of VEGF and normal intermediate layer blood vessel development.
genes, the team has shown that B. theta helps guide the normal development and functioning of the intestines — including the growth of blood vessels, the proper turnover of epithelial cells, and the marshaling of components of the immune system needed to keep less well behaved bacteria at bay.
«We need more research to better understand how to help people who have had adversity in childhood prevent or delay the development of heart and blood vessel diseases.»
When functioning properly, OTULIN regulates the development of new blood vessels and mobilization of cells and proteins to fight infection.
Not all children who grow up facing adversity develop diseases of the heart and blood vessels, a finding that suggests the existence of a range of biological, environmental, cultural and social factors that may help reduce risk and prevent disease development.
Continuing, Bangsbo asserts that, «Furthermore, there was a positive development in relation to levels of substances vital to blood vessel function, including a 20 % decrease in markers associated with arteriosclerosis.»
In an experimental model of malaria in pregnancy, supplementing the diet of pregnant mice with L - arginine increased blood vessel development in the placenta and reduced low birth weight / preterm birth and stillbirth.
«The discovery of ferroelectricity in blood vessel walls adds an important dimension to the biophysical properties of blood vessel wall, which could lead to the development of new methods in prevention and treatment of cardiovascular diseases,» Liu and collaborators write.
Zebrafish have emerged as an important vertebrate model for cardiovascular research for a number of reasons, including the ability to regenerate its heart if damaged, and because the transparency of the embryos allows easy observation of internal processes like blood vessel development.
Blood vessel development is critical for the growth of any solid tumor, such as breast, colon or lung cancer.
Professor Geoff Pilkington, study co-author and Head of the Brain Tumour Research Centre, said: «Although this work is still at an early stage, we have demonstrated key elements that are associated with tumour cell binding to blood vessels and this may provide a target for future drug development to prevent the development of secondary tumours in the brain.
Cell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invasion.
The nerve cells of the central nervous system (CNS), which is composed of the spinal cord, the brain, and the retina, must be supplied with sufficient oxygen and nutrients through the blood vessel system during development and their subsequent function.
«Moreover, there is an active bidirectional communication between the nerve cells and the blood vessels to ensure the proper development and maintenance of an organ as complex as the brain,» reports Carmen Ruiz de Almodóvar.
His team have begun recolonising the primate scaffolds with human cells that line blood vessels, the first step towards human - scale biolimb development, and have started experiments using human myoblasts in rats instead of the mice ones.
«Secret alter ego of well - known protein fights leaky blood vessels: Surprise discovery of a new pathway governed by Notch signaling protein opens door for better drug development.»
While the use of antiangiogenesis drugs that block the growth of new blood vessels can improve the treatment of some cancers, clinical trials of their ability to prevent the development of new metastases have failed.
Using a mouse model of cancer that provides direct microscopic access to lymph nodes, they first found that the initiation and growth of node metastases did not involve the development of new blood vessels.
The group investigated the ability of human neural cells to aid the formation of blood vessels during brain development.
«If we could prevent development of the new blood vessels in the cancer tissue driven by these signals, tumor growth and metastasis can be slowed down or prevented.»
It is also known that the interaction between blood vessels and neurons is essential for the correct development of the brain, as it allows the correct supply of oxygen and nutrients to neural cells and remove potentially harmful molecules.
Known to be linked to pain sensitivity and currently used in the development of painkillers, this is the first time the TRPA1 gene has been implicated in the response of blood vessels in the skin to cold.
They first induced angiogenesis in mice through the injection of a growth factor called FGF - 2 and measured blood vessel development in the presence and absence of synthesised IP5.
To understand the mechanisms responsible for the development of renal insufficiency in such children, the researchers from Monash University and the University of Queensland examined the impact of a reduction in fetal renal mass on the mechanisms regulating kidney and blood vessel function.
«Finding a way to control angiogenesis not only provides a target for the development of anti-cancer therapies, but may also prove useful in similarly starving abnormal blood vessel growth elsewhere in the body, like in diabetic eye disease.»
Scientists could also use the printed tissue constructs to shed light on activities of living tissue that require complex architecture, such as wound healing, blood vessel growth, or tumor development.
With potential therapeutic implications, Stainier and a colleague also recently discovered that endothelial cells, which line the blood vessels, play a critical role in inducing the development, or proper differentiation, of red blood cells, the transporters of oxygen.
Improved understanding of mechanisms of blood vessel injury promotes development of new and innovative treatments.
On Friday I discussed one of the recent developments in the science of tissue engineering, the development of artificial blood vessels for transplant by Dr. Laura Niklason of Yale University.
During the foetal period, temporary blood vessels, so - called hyaloid vessels, play an important role for the development of the eye.
Thus, dissemination of cancer cells occurs after prolonged tumor development and following access to neighboring blood vessels via transit through stromal tissue.
Irish scientists have discovered that abnormalities in the blood vessels of the brain may have a key role to play in the development of schizophrenia.
Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in blood vessel output power and significant increase in blood vessel ageing level and remaining blood volume 25 minutes later, as markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and found adverse histopathological effects on brain cells.96
«Instead of treating patients after these abnormal blood vessels form in the eye, we may be able to give patients eye drops or systemic medications that prevent their development in the first place.»
-- Development of the circulatory system.While doing cardio more oxygen is pushed through the blood vessels, making them bigger in size and resulting in a greater number of blood vessels.
In pregnancy, calcium is needed to support development of healthy teeth, heart, blood vessels, and more in your baby.
Apigenin stopped formation of new blood vessels, thus delaying, and at times blocking, tumour development.
The chronically stressed mice had decreased immune function and experienced tumor development significantly earlier than the non-stressed mice.16 Other mouse studies of ovarian cancer showed that chronic stress resulted in increased cancer growth as well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risk.
A diet high in saturated and trans fats and low in antioxidants can damage blood vessel walls to cause an immune response related to inflammation and the development of cardiovascular ailments.8, 9,10 Low - grade inflammation in older individuals has been shown to contribute to fat accumulation, insulin resistance, and inflammatory - related diseases.11
In addition to the niacin it supplies, brown rice may also help raise blood levels of nitric oxide, a small molecule known to improve blood vessel dilation and to inhibit oxidative (free radical) damage of cholesterol and the adhesion of white cells to the vascular wall (two important steps in the development of atherosclerotic plaques).