Sentences with phrase «development of diseases»

Numerous studies suggest that maternal stress experienced in utero influences programming of key physiological systems that contribute to childhood disease57 and that nonoptimal early childhood environments and caregiving experiences also influence these processes.58 - 61 Specifically, emerging data implicate the disruptive impact of stress on the HPA, autonomic, neuroendocrine, and immune systems.1, 3,7,57,62 Disruptions of these stress regulatory systems may, in turn, be linked to immune dysregulation, increasing vulnerability to the development of diseases such as asthma.

Because older pets often have different nutritional requirements, these special foods can help keep your pet's weight under control and reduce consumption of nutrients that are risk factors for the development of diseases, as well as organ - or age - related changes.

Abnormal activation of signals often trigger or facilitate the development of diseases, including cancer.

Rabbits left intact are at risk for the development of diseases of the reproductive tract.

«Population studies have consistently supported a protective role of nuts against cardiometabolic disorders such as cardiovascular disease and type 2 diabetes, and we know that inflammation is a key process in the development of these diseases,» said corresponding author Ying Bao, MD, ScD, an epidemiologist in BWH's Channing Division of Network Medicine.

Disturbances of hormones during infant development can also influence the likelihood of the development of diseases or dysfunctions later in life.

«Future research will reveal the molecular mechanisms behind this immediate stress response and elucidate its role in the development of diseases associated with chronic sleep loss,» said Katrin Ackermann, PhD, the study's lead author.

Sakuyama H and others, «Influence of gestational salt restriction in fetal growth and in development of diseases in adulthood».

The theory proposed by Professor Khavinson is based on the underlying assumption that changes in gene expression result in decreased protein synthesis, eventually leading to aging and the development of diseases.

«It is known that calorie restriction extends life and delays the development of diseases during ageing and we wanted to see what effect calorie restriction had on the circadian clock».

Initiated in February 1998, and covering up to 12 common diseases, the five - year collaboration is focusing on the discovery of gene variants that predispose and / or contribute to the development of these diseases, with a major emphasis on six of them.

For a long time it has been known that the protein TOR — Target of Rapamycin — controls cell growth and is involved in the development of diseases such as cancer and diabetes.

Discoveries such as this raise the possibility that changes in protein synthesis are necessary for the development of those diseases.

There are currently limited treatments to prevent or delay declining cognition or dementia due to vascular disease, but if risk is identified early, then development of these diseases might be slowed with lifestyle adjustments and treatments for risk factors like blood pressure.

Jianguo Fang and colleagues note that mounting evidence suggests that oxidative damage to neuronal cells contributes to the development of diseases that originate in the brain.

In this way, it prevents the development of diseases and stimulates plant growth in a single application.

At the same time, this is also knowledge that can help to develop drugs which can stop or slow the development of the diseases,» explains Morten Gersel Stokholm about the sleep disorder which most often affects persons aged 50 - 70, and more frequently men than women.

Nonetheless, some ERVs may still retain the ability to become reactivated and are implicated in the development of diseases.

Genotoxicity is associated with the development of diseases and is a critical mechanism responsible for many types of cancer caused by smoking and secondhand smoke exposure.

These techniques are key to understanding the molecular mechanisms underlying cell function in healthy and diseased individuals and the development of diseases like cancer.

BUSM researchers also discussed in Genetics & Epigenetics (May 2014) how epigenetic modifications play a role in the development of diseases including cancer, cardiovascular, metabolic, neurologic and pulmonary disorders.

«Population studies have consistently supported a protective role of nuts against cardiometabolic disorders such as cardiovascular disease and type 2 diabetes, and we know that inflammation is a key process in the development of these diseases,» said corresponding author Ying Bao, MD, ScD, an epidemiologist in BWH's Channing Division of Network Medicine.

Baby soaps and shampoos, especially those with fragrance and which contain sodium lauryl sulfate, are factors in the development of the disease.

This in turn predisposes to the development of disease.

Scientists have shifted from studying single molecules to investigating large complexes of interacting biological macromolecules involved in processes such as metabolic pathways, gene expression, and development of disease.

Professor Fitt continued: «We know that the weather plays a big part in the development of the disease on the wheat crops — the incidence of the disease is determined by temperature and the occurrence of wet weather at the flowering or anthesis of the wheat crops.»

The study shows showed that the PSC patients had lower coffee consumption both currently and in the early adulthood, suggesting that coffee consumption could protect against the development of the disease.

A team at Northwestern University's Feinberg School of Medicine in Chicago reports that isradipine (brand name DynaCirc), a drug currently prescribed to reduce high blood pressure, may block the death of neurons in patients with advanced cases of Parkinson's and may also be able to prevent the development of the disease.

«The peanut genome project will lead to reduction in production costs through development of disease - resistant varieties and improved yield for farmers, speed of selection and release of new varieties for breeders and potential for improvement of nutritional value of peanuts for consumers,» Nwosu said.

Up to now researchers thought that the astrocytes migrated towards the amyloid plaques and devoured them, so that reinforcing their activity could be a good remedy against development of the disease.

However, the role of this deletion in the development of the disease remained unclear going into this study.

Approximately 42 % of children in the study with MRI findings of MS developed the first clinical symptoms of the disease about two years after the abnormal MRI, which shows a faster development of the disease than has been reported in adults.

Prof. Mandelboim and his research collaborators found that the NKp46 receptor present on Natural Killer or NK cells (an essential part of the immune system) play a critical role in the development of the disease in mice.

It not only makes existing heart conditions worse but also contributes to development of the disease.

If confirmed by clinical research, the data points to the possibility that early pharmaceutical intervention could make a significant difference in the development of the disease.

An active international research has been carried out for several years in order to identify candidate genes which explain the origin and development of the disease.

Dr Dumas emphasises that, as this is an observational study, the findings can not show that disinfectants cause COPD, only that there is an association between some disinfectants and the development of the disease.

Past research had revealed the presence of OPTN defects in people with both inherited and sporadic forms of ALS, but scientists were not sure whether and how OPTN was involved in the development of the disease.

Recent years have brought about the discovery of the fundamental contribution of epigenetics to the development of disease.

However, much of the research conducted to date has been post-mortem, which does little to help researchers understand the early development of disease.

«The role of these mutations in the onset and development of disease is still unknown,» says Johan Tisserand, postdoctoral research and co-author of the study who is continuing with the project.

In this week's Science (21 October, p. 735) a team from the biotech company Amgen Inc. in Thousand Oaks, California, reports finding an enzyme called b - secretase, which has long been suspected of playing a key role in the development of the disease.

Such diversity research has already led to the development of disease - resistant strains and the identification of crops that could thrive under higher carbon dioxide conditions, as well as new ways to deploy diversity.

Early identification of patients with risk factors for a number of disorders would allow for early treatment that could potentially stop the development of disease in its earliest stages.

Given the ability of stem cells to divide indefinitely, investigators have debated their possible role in the development of the disease.

About 20 to 30 percent of colorectal cancer patients appear to have a familial risk and a minority has a genetic mutation that contributed to the development of the disease.

Dr Alexander Mazein, lead author of the study from the European Institute for Systems Biology and Medicine, commented: «In - depth understanding of asthma means redefinition of asthma subtypes based on the mechanisms that lead to the development of the disease.

Large numbers of these pileups and double - strand breaks are lethal to the cell, serving as a jumping off point for the development of disease.

The mouse version of the IAPP protein can not clump — and mice don't develop type 2 diabetes, a sign that the accumulation of IAPP is important in the development of the disease, says Soto.

Research has shown that lifestyle habits, such as exercise and nutrition, play a crucial role in the development of the disease.