Sentences with phrase «development of microcephaly»

Not exact matches

The scientists rescued the microcephaly during mouse embryonic development by removing a protein that caused the loss of stem cells.

Neither set of pups developed microcephaly, which Diamond says could be because the researchers infected the mothers so early during pregnancy that not much brain development had yet occurred.

The finding of virus in the brain could also be important, since the most devastating impact of the current outbreak in Brazil appears to be children of infected mothers born with microcephaly — abnormally small heads and, in some cases, incomplete brain development.

Zika virus infection during pregnancy can result in microcephaly and other serious birth defects in the fetus, making the development of a safe and effective vaccine a global health priority.

If that happens during the key phases of brain development in the first 3 to 4 months of pregnancy, the overall size of the brain would be dramatically reduced, leading to microcephaly.

The approach enabled a wide range of studies of human brain development, including implicating a new class of neural stem cell recently discovered by the lab in the evolutionary expansion of the human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly in infants infected in utero.

In both of these scenarios, neural stem cells, which are crucial for normal neural development, are lost, leading to microcephaly.

In the cells of babies with microcephaly, three genes known to be involved in neural development were less active.

Future studies of these cells are expected to shed light on developmental diseases such as autism and schizophrenia and malformations of brain development, including microcephaly, lissencephaly and neuronal migration disorders, they say, as well as age - related illnesses, such as Alzheimer's disease.

Based on that, we recommend using the term congenital Zika syndrome instead of microcephaly associated with Zika virus infection, which involves a spectrum of changes, including other neurological and fetal development manifestations.

We have shown that the presence of extra centrosomes in proliferating embryonic neural stem cells is sufficient to impair brain development and culminates in microcephaly (small brains) at birth.

The main birth defect attributed to Zika is microcephaly, a rare neurological condition in which an infant is born with a much smaller head — an effect of abnormal brain development.

Understanding Zika's mechanisms will illuminate how viral infection leads to birth defects such as microcephaly, a condition marked by an abnormally small head and brain size, and could inform the development of therapies and vaccines, the study authors said.

Zecavati is a pediatric neurologist who treats children with microcephaly and can describe the neurologic signs and symptoms associated with microcephaly, including the various causes of microcephaly and how microcephaly affects a child's development and cognitive abilities.

Working in laboratory mice, they injected the most abundant of these small RNAs into the mouse brain to assess the impact of each on brain development, including whether they caused microcephaly.