Importantly,
the development of a new animal model for Dravet syndrome based on reduced CHD2 expression might help to find effective treatments that could improve the lives of thousands of people suffering from Dravet syndrome and perhaps other genetic epilepsies.»
Not exact matches
«The
animal terminal will set
new international airport standards for comprehensive veterinary, kenneling and quarantine services,» John J. Cuticelli Jr., Founder
of Ark
Development LLC and Racebrook Chairman, said in a statement.
Since the human developed out
of the subhuman, and since this process
of development was a continuous one, it is essential to understand what man has in common with other
animals, as well as to describe the threshold that marked his appearance as something genuinely and decisively
new.
Say we have a population
of animals which has to meet some
new challenge offered to it by an altered environment; there may be some individuals in the population whose
development is changed by the environment in a way which makes them better able to deal with the challenge — they show a capacity for adaptive modification.
Grants available for the
development of new or improved control tools and technologies to help farmers and land managers reduce the harmful impacts
of established pest
animals and weeds.
This
new development in
animal feed attracted the attention
of Old Mother Hubbard and
animal - feed leviathan, Nestle Purina Petcare.
Alternative protein sources may include the use
of by - products currently viewed as waste or the
development of new protein sources from plants, lower order
animals, or single - cell organisms with a lower environmental impact compared with typical
animal - based protein sources.
PMTCT strategic vision 2010 — 2015 -(2010) WHO - Preventing mother - to - child transmission
of HIV to reach the UNGASS and Millennium
Development Goals HIV and infant feeding: Update (2007) Based on the technical consultation held on behalf
of the Inter-agency Task Team (IATT) on Prevention
of HIV infections in pregnant women, Mothers and their Infants, Geneva, Switzerland, 25 - 27 October 2006 HIV and infant feeding:
new evidence and programmatic experience (2007) Report
of a technical consultation held on behalf
of the Inter-agency Task Team (IATT) on Prevention
of HIV infections in pregnant women, Mother and their Infants, Geneva, Switzerland, 25 - 27 October 2006 WHO HIV and infant feeding technical consultation - consensus statement (2007) Held on behalf
of the Inter-agency Task Team (IATT) on Prevention
of HIV infections in pregnant women, mothers and their infants Home - modified
animal milk for replacement feeding: is it feasible and safe?
We do not cover
developments of interest only to specialists, such as
new animal models
of a disease or the opening
of new science research centres.
With the harvested follicles, investigators such as James V. («Vince») Gruber, global director
of research and
development at Lonza Consumer Care, can test the effectiveness
of new hair and skin products without relying on laboratory
animals.
The changes shown through 2050 could lead to lost habitat, the isolation
of some species and the rise
of «dispersal barriers» — like a wall
of new development that prevents plants and
animals from migrating.
Larsson is at the forefront
of merging paleontology and molecular biology in an effort to connect major evolutionary changes — the
development of new species and
new characteristics,
new shapes and structures,
new kinds
of animals — to changes in specific genes and in how those genes are regulated.
The journal provides cutting - edge research including results from
animal models that are likely to apply to patients, studies in human tissue that provide
new information about therapies or disease, and innovative reports
of drug discovery and
development.
Michael Kelemen, a recruiter and host
of the Recruiting
Animal show, a call - in career
development and recruiting radio show on BlogTalkRadio, told Science Careers, «These days it's about being first to hear about
new jobs and making yourself stand out as a job candidate.
With the move to India, Colleen left the lab bench so that she could coordinate the
development of facilities at inStem; this included
new laboratory space and an
animal facility housing mice, rats, fish, and frogs.
In a
new animal study, University
of Missouri researchers examined how the
development of obesity and insulin resistance contribute to bone - fracture risk and whether exercise prevents weight gain and diabetes and protects bone health.
«With further
development, the
new microendoscope could be used to image neuron activity in previously inaccessible parts
of the brain such as the visual cortex
of primate
animal models,» said Ohayon.
The first
animal trials
of the pills have examined the impact
of low and high - fiber diets on intestinal gases and offer
new clues for the
development of treatments for gut disorders.
Very high frequencies, up to the 100 MHz range, enable resolutions in the µm - range, e.g., for materials testing or the imaging
of small
animals that is needed with the
development of new technologies.
Importantly, these devices also will open up
new approaches to drug
development not possible with
animal models today, such as personalized medicines and
development of therapeutics for specific genetic subpopulations using chips created using cells from particular patients.»
In past studies to develop a
new animal model for the brain events that support motor
development, neurophysiologist Martin Garwicz
of Lund University in Sweden and his colleagues discovered that the schedules by which ferrets and rats acquire various motor skills, such as crawling and walking, are strikingly similar to each other; the progress simply happens faster for rats.
Discoveries will lead to
new hypotheses and experiments that will further our understanding
of animal development and function — and how both can go awry.
«Although this is basic scientific research using
animal models, these studies are shedding light on the molecular mechanisms that control male fertility, and are helping us to better understand the causes
of many cases
of infertility and enabling
new horizons to be opened up in the
development of therapeutic targets and strategies to combat it,» explained Dr Subirán.
So - called assortative mating, in which
animals that look similar are more likely to mate with each other, is one
of the causes
of new species
development.
In a
development that could lead to a
new generation
of drugs to precisely treat a range
of diseases, scientists from the Florida campus
of The Scripps Research Institute (TSRI) have for the first time designed a drug candidate that decreases the growth
of tumor cells in
animal models in one
of the hardest to treat cancers — triple negative breast cancer.
The original aim
of the treaty was to ensure that Third World nations would be rewarded if the plants and
animals found within their borders were used in the
development of new drugs.
«We used to think that close integration
of animal and crop husbandry» was a later
development, he says, but the
new research indicates «that it goes back to Europe's first farmers.»
New gene - editing technologies such as CRISPR have sped the development of new crop varieties and animals, but products based on engineered organisms sometimes face a web of complex and overlapping regulations before they can reach the mark
New gene - editing technologies such as CRISPR have sped the
development of new crop varieties and animals, but products based on engineered organisms sometimes face a web of complex and overlapping regulations before they can reach the mark
new crop varieties and
animals, but products based on engineered organisms sometimes face a web
of complex and overlapping regulations before they can reach the market.
Our finding
of similarity in clinical progression between human patients and Huntington's disease monkeys suggests monkeys could become a preclinical, large
animal model for the
development of new treatments.»
The cellular model
of the airway mucosa could provide insight into biological and pathophysiological effects that conventional cell cultures or
animal models do not capture, and help lead to the
development of new therapeutics.
Whitmer said one theory stemming from
animal research is that metformin may play a role in the
development of new brain cells (neurogenesis).
IDMIT will contribute 1) To the
development and validation
of assays based on flow cytometry and mass cytometry for the evaluation
of immune responses in humans and
animal models; these tools will be particularly relevant for the identification
of signatures
of vaccine efficacy; 2) To the
animal model platform, in particularly by providing access to NHP models and to
new technologies for in vivo imaging infections and host responses; 3) To networking activities, in particular by organising a workshop on in vivo imaging.
All together INRA facilities power up (1) Research in multi-disciplinary domains through academic and industrial collaborations for the
development of large
animal models, therapeutics or
new imaging devices, and (2) Training under several topics (biocontained experiments, introduction
of new imaging methods for large
animal models etc.), welcoming external teams which do not possess such an instrumental park for Transnational access.
GLP regulations and guidelines for the conduct
of preclinical testing ensure the quality and integrity
of data submitted in support to the
development of new treatments, foster mutual acceptance
of data in the international community, serves to minimise redundant testing, minimize
animal use and maximise protection
of human health.
Mild oxygen levels in shallow seas but oxygen - poor deep oceans lasted for some 1.3 billion years during a time that has been dubbed the «Boring Billion» but eventually led to the
development of mitochondria that now power multicellular planet and
animal life (Nick Lane,
New Scientist, February 10, 2010; Rachel Ehrenberg, Science News, September 29, 2009; Johnston et al, 2009; and H.D. Holland, 2006).
Although further refinement and testing is needed, Dr. Burgess said the
new techniques have the potential to speed the production
of many different types
of transgenic
animal models that will shed
new light on human
development and disease.
Although atmospheric oxygen soon recovered again as photosynthesis and weathering reached a
new balance, at about 10 per cent
of present - day levels, the oxidative weathering
of sulphides on land filled the oceans with sulphate which created abundant food for a group
of bacteria that filled the oceans with sewer gas (hydrogen sulphide) toxic to oxygen - loving lifeforms (delaying the
development of eukaryotic plants and
animals) and turned them «into stinking, stagnant waters almost entirely devoid
of oxygen.»
Rutaganira expects her studies will spark
new understanding
of animal development, physiology, and disease.
Vice-President
of Research & Scientific
Development, Robert Lanza, M.D.'s, provocative
new theory that time and space do not exist as physical realities independent of humans (and animals) has been published in a feature article «A New Theory of the Universe» in the Spring issue of «The American Scholar», one of the nation's leading literary and intellectual publicatio
new theory that time and space do not exist as physical realities independent
of humans (and
animals) has been published in a feature article «A
New Theory of the Universe» in the Spring issue of «The American Scholar», one of the nation's leading literary and intellectual publicatio
New Theory
of the Universe» in the Spring issue
of «The American Scholar», one
of the nation's leading literary and intellectual publications.
The CCFA Genetics Initiative seeks to deliver validated pathway models
of IBD disease mechanisms,
new animal models for analysis and
development, chemical probes
of relevant pathways,
new proteins and pathway targets, recruitment
of new IBD investigators, and a tested paradigm for rapid analysis and cure for Crohn's disease.
Professional Experience 1983 — 1986 Research / Teaching Assistant, Exercise Physiology, University
of Texas, Austin TX 1986 — 1990 Assistant Instructor / Research Assistant, Cell Biology, Developmental Biology, and Vertebrate Physiology, University
of Texas, Austin TX 1993 — 1994 Visiting Assistant Professor, Department
of Animal Sciences, Oregon State University 1994 — 1996 Technical Services Advisor, Genetic Resources, The Jackson Laboratory, Bar Harbor ME 1996 — 1998 Manager, Technical Services, The Jackson Laboratory, Bar Harbor ME 1997 — 1998 Assistant Professor, Adjunct,
New Mexico Highlands University, Las Vegas NM 1998 — 2000 Senior Technical Information Scientist, The Jackson Laboratory, Bar Harbor ME 2000 — 2002 Senior
New Models
Development Scientist, The Jackson Laboratory, Bar Harbor ME 2002 — 2004 Associate Director
of Genetic Resources, The Jackson Laboratory, Bar Harbor ME 2004 — 2005 Associate Research Scientist, The Jackson Laboratory, Bar Harbor ME 2004 — 2009 Assistant Professor, Dept.
of Biology,
New Mexico Highlands University, Las Vegas NM 2009 — 2014 Associate Professor, Dept.
of Biology,
New Mexico Highlands University, Las Vegas NM 2014 — present Professor, Dept.
of Biology,
New Mexico Highlands University, Las Vegas NM
In addition to a detailed study
of the mudskipper and
development of a robot model that used the
animal's locomotion techniques, the study also examined flow and drag conditions in representative granular materials and applied a mathematical model incorporating
new physics based on the drag research.
His research utilizes molecular biology, cell culture, and
animal models to study your body's cannabinoid system in an attempt to further our understanding
of Cannabis as a medicine, and possibly lead to the
development of new drug compounds.»
Animal studies, whether for the
development or production
of new medicines, for physiological studies, for studying environmental effects or for the testing
of chemicals or
new food additives, has to be carried out in compliance with EU legislation.
It puts into effect, and in some ways exceeds, European Union Directive 86 / 609 / EEC (regarding the protection
of animals used for experimental and other scientific purposes) and offers a high level
of protection to
animals whilst recognising the need to use
animals in medical research, the
development of new medicines and scientific testing.
A
new analysis
of one
of the most bizarre - looking fossils ever discovered has definitively sorted its head from its tail, and turned up a previously unknown ring
of teeth, which could help answer some
of the questions around the early
development of moulting
animals.
It puts into effect, and in some ways exceeds European Union Directive 2010 / 63 / EU (regarding the protection
of animals used for experimental and other scientific purposes) and offers a high level
of protection to
animals whilst recognising the need to use
animals in medical research, the
development of new medicines and scientific testing.
As part
of the SFI Investigators Programme 2016 call, SFI is providing applicants with the opportunity to seek funding to support the
development and validation
of new tests, models and approaches not involving the use
of live
animals and / or addressing the principles
of the 3Rs (Replacement, Reduction and Refinement).
Partnership to adopt Organ - Chips to provide human - relevant data in drug discovery and
development aiming to reduce
animal testing, and to implement personalized safety testing
of new drug candidates
In 2013, Peterson and his colleagues Joanna Yeh and Keith Joung were first to use the
new technology to engineer a
new strain
of animal — a zebra - fish missing the GSK3ß gene, which encodes an enzyme involved in energy metabolism and the
development of cell and body structures as an embryo grows.