Dr. Rebecca Vega Thurber received her doctorate in 2005 from Stanford University where she studied
developmental cell signaling pathways in sea urchin larvae.
Not exact matches
They found that these genetic differences were tied to several important
developmental and
cell signaling pathways.
Examples of these include
cell proliferation, intracellular targeting,
cell polarity, membrane traffic,
cell migration, stem
cell biology, chromatin regulation and function, differentiation, morphogenesis and biomechanics, and regeneration and cellular homeostasis, as well as
developmental roles of genes, cellular structural dynamics, and
signaling pathways.
Upon T
cell receptor
signaling, these
cells initiate a differentiation program that includes complex changes in CD4 and CD8 expression, allowing identification of transitional intermediates in this
developmental pathway.
The notion that a Nanog positive, ICM - like population of high probability self - renewing
cells is a
developmental ground state is supported by the expansion of this state in the presence of a blockade on the major
signalling pathways known to promote ES
cell differentiation, the MAP kinase / ERK cascade and GSK3β [42], [50].
Components of the major metazoan
developmental signalling pathways, as well as classes of
developmental transcription factors, are mostly present in Amphimedon and absent from Monosiga and other non-metazoan genomes13, 14,16,27,29, suggesting that ontogenetic development, including primary germ
cell formation (Supplementary Note 8.4), originated on the metazoan stem3, 11,12.